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Pioglinet
National Laboratories Ltd.
Generic: Pioglitazone
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Pioglinet.
CONSULT YOUR DOCTOR
Pioglinet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Pioglinet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with Pioglinet
SAFE
Pioglinet does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Pioglinet is safe to use in patients with kidney disease. No dose adjustment of Pioglinet is recommended.
Use of Pioglinet is not recommended in patients undergoing dialysis.
CAUTION
Pioglinet should be used with caution in patients with liver disease. Dose adjustment of Pioglinet may be needed. Please consult your doctor.
Use of Pioglinet is not recommended in patients with severe liver disease.
Medicine Overview of Pioglinet 15mg Tablet
Introduction
Pioglinet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness. Pioglinet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working. Keep taking this medicine, even if you...
... Show moreUses of Pioglinet
- Type 2 diabetes mellitus
Side effects of Pioglinet
Common
- Weight gain
- Blurred vision
- Respiratory tract infection
- Numbness
- Bone fracture
How to use Pioglinet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pioglinet may be taken with or without food, but it is better to take it at a fixed time.
How Pioglinet works
Pioglinet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.
What if you forget to take Pioglinet?
If you miss a dose of Pioglinet, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Pioglinet helps to control blood sugar level and avoid long-term complications.
- Take it only as per dose and duration suggested by your doctor.
- You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Pioglinet.
- Full effects may be visible after several weeks of starting Pioglinet. Keep taking it as prescribed by your doctor.
- Monitor your blood sugar level regularly while taking this medicine.
- Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
- Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.
Brief Description
Indication
Type 2 DM
Administration
May be taken with or without food.
Adult Dose
Oral
Type 2 diabetes mellitus
Adult: 15 mg once daily.
Elderly: No dosage adjustment needed.
Hepatic impairment: Moderate to severe: Avoid.
Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Hypersensitivity. Type 1 diabetes mellitus, symptomatic or history of heart failure, diabetic ketoacidosis, childn <18 yr. Lactation.
Mode of Action
Pioglitazone is as a potent and highly selective agonist for the peroxisome proliferator activated receptor-? (PPAR-?). Activation of these receptors promotes the production of gene products involved in lipid and glucose metabolism. It also improves insulin response to target cells w/o increasing the pancreatic secretion of insulin.
Precaution
I. Liver Enzyme must be monitored regularly II. History of heart failure and MI should be verified III. Incidence of bladder cancer should be verified IV. Not to be used for elderly patients V. Not to be used continuously more than one year VI. Use only by Specialist advice. Increased risk of hypoglycaemia when used with insulin or oral hypoglycaemics. Oedema, congestive heart failure, hepatic dysfunction, jaundice, anaemia. May cause ovulation in premenopausal, anovulatory women. Monitor liver function before and during treatment. Monitor glycaemic control. Pregnancy. Caution when oral contraceptives or hormonal replacement therapy is used in diabetics due to...
... Show moreSide Effect
>10%
Edema when used in combination with sulfonylurea or insulin (<27%),Hypoglycemia (<27%),Upper respiratory infection (13%)
1-10%
Headache (9%),Heart failure (up to 8%),Sinusitis (6%),Fracture of bone (5%),Pharyngitis (5%),Myalgia (5%)
Frequency Not Defined
Aggravated diabetes,Diabetic macular edema,Hepatic failure (rare),Increased cholesterol,Decreased serum triglycerides,Hematocrit/hemoglobin,Bladder cancer,Decreased visual acuity,Dyspnea,Increased transaminases,Pharyngitis,Sinusitis,Weight gain
Interaction
Increased risk of oedema w/ insulin, metformin and sulfonylureas. Increased plasma levels w/ gemfibrozil and ketoconazole. Decreased plasma levels w/ rifampicin.
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