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Onbrez Breezhaler 300
Nevian Lifescience PLC
Generic: Indacaterol Maleate
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Onbrez Breezhaler 300.
CONSULT YOUR DOCTOR
Onbrez Breezhaler 300 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Onbrez Breezhaler 300 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medicine Overview of Onbrez Breezhaler 300mg Capsule
Introduction
Onbrez Breezhaler 300 is used for the treatment of asthma and chronic obstructive pulmonary disorder(COPD) ,a lung disorder in which flow of air to the lung is blocked. It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe. Onbrez Breezhaler 300 is only for the inhalational purpose, so do not swallow the capsule. The first dose is given under medical supervision to prevent the side effects happen during first use. For better results, it is suggested to take it at the same time every day. The dose and how often you...
... Show moreUses of Onbrez Breezhaler 300
- Asthma
- Chronic obstructive pulmonary disease (COPD)
Side effects of Onbrez Breezhaler 300
Common
- Runny nose
- Headache
- Cough
- Dizziness
How to use Onbrez Breezhaler 300
Take this medicine in the dose and duration as advised by your doctor. Check the label before use.
How Onbrez Breezhaler 300 works
Onbrez Breezhaler 300 is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. This makes breathing easier.
What if you forget to take Onbrez Breezhaler 300?
If you miss a dose of Onbrez Breezhaler 300, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- This medicine is for inhalation only. The tablet should not be swallowed.
- It should be taken at the same time each day.
- It does not work right away and should not be used to relieve sudden breathing problems.
- Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Brief Description
Indication
Indacaterol Maleate is indicated for maintenance bronchodilator treatment of airflow obstruction in adult patients with, chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Adult Dose
Inhalation
Maintenance therapy in chronic obstructive pulmonary disease
Adult: As inhal cap: Inhale 75-150 mcg once daily using inhaler.
Max: 300 mcg once daily.
Hepatic impairment
No dose adjustment is required for patients with mild and moderate hepatic impairment.
There are no data available for use of Onbrez Breezhaler in patients with severe hepatic impairment.
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment
No dose adjustment is required for patients with renal impairment.
Contraindication
All LABA are contraindicated in patients with asthma without use of a long-term asthma control medication. Indacaterol is not indicated for the treatment of asthma. Indacaterol is contraindicated in patients with a history of hypersensitivity to indacaterol or to any of the ingredients.
Mode of Action
Indacaterol is a long acting β2-adrenergic agonist. It relaxes the bronchial smooth muscle by selective action on β2-receptor which acts locally in the lungs and w/ little effect on heart rate.
Precaution
Not intended for treatment of asthma and acute deterioration of COPD. Patient w/ acutely deteriorating COPD, thyrotoxicosis, seizure disorders, DM, hypokalaemia, CV disorders esp coronary insufficiency, cardiac arrhythmias or HTN. Pregnancy and lactation.
Lactation: Unknown whether distributed in human breast milk; use caution
Side Effect
>10%
Post-inhalation cough (24% compared with 7% on placebo)
1-10%
Cough (6.5%),Nasopharyngitis (5.3%),Headache (5.1%),Nausea (2.4%),Oropharyngeal pain (2.2%)
Potentially Fatal: Asthma-related deaths.
Interaction
Potentiated adverse effects w/ other sympathomimetic agents; possible hypokalaemic effect w/ methylxanthine derivatives, steroids or non-K-sparing diuretics. Other long-acting beta2-adrenergic agonists or medicinal products containing long-acting beta2-adrenergic agonists. Inhibition of the key contributors of indacaterol clearance, CYP3A4 and P-gp.
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