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Parten Plus

Tablet-(12.5mg+50mg)
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Jayson Pharmaceuticals Ltd.chevron-right

Generic: Hydrochlorothiazide + Losartan Potassium

Stock AvailableStock: Available
1 Tablet
৳5.45
৳6
9% OFF
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Medicine Overview of Parten Plus 12.5mg+50mg Tablet

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Introduction

Parten Plus is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. You can take Parten Plus with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase. The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhoea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine. This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

Uses of Parten Plus

  • Hypertension (high blood pressure)

Side effects of Parten Plus

Common
  • Nausea
  • Taste change
  • Upset stomach
  • Diarrhea
  • Headache
  • Dizziness
  • Weakness
  • Decreased blood pressure
  • Increased blood uric acid
  • Increased blood lipid level
  • Glucose intolerance
  • Electrolyte imbalance

How to use Parten Plus

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Parten Plus may be taken with or without food, but it is better to take it at a fixed time.

How Parten Plus works

Parten Plus is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Quick Tips

  • You have been prescribed Parten Plus for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Parten Plus may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Use of Parten Plus during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.

Brief Description

Indication

Hypertension, Stroke, risk reduction of hypertensive or LVH patients

Adult Dose

Hypertension Initial: 50 mg/12.5 mg PO qDay If dose titrated upward, do not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q12hr Decrease losartan to 25 mg PO qDay initially if volume depleted

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment CrCl <30 mL/min: Do not use thiazide-containing products; loop diuretic preferred CrCl >30 mL/min: No dosage adjustment required

Contraindication

Pregnancy, lactation; intravascular volume depletion.

Mode of Action

Hydrochlorothiazide increases renal excretion of sodium and chloride and reduces cardiac load. Losartan is an angiotensin II receptor (type AT1) antagonist antihypertensive which acts by blocking the actions of angiotensin II of renin-angiotensin-aldosterone system. The drug and its active metabolite selectively block the vasoconstrictor and aldosterone secreting effects of angiotensin II. The two drugs exert additive effects in hypertension.

Precaution

Existing electrolyte disturbances; hepatic cirrhosis; severe hepatic failure; oedema; elderly (>75 yr); renal impairment; hepatic impairment; diabetes, gout, hyperlipidaemia; hyperuricaemia; ECG: LVH and/or ventricular ectopics extrasystoles); volume depleted patients; patients on diuretics and salt restriction; renal artery stenosis; aortic and mitral stenosis. Monitor potassium concentration. Discontinue before performing tests for parathyroid function. Lactation: Discontinue drug or do not nurse

Side Effect

>10% Losartan Fatigue (14%),Hypoglycemia (14%),Chest pain (12%),Cough, incidence higher in previous cough related to ACE therapy (3-11%) 1-10% Losartan Diarrhea (2-10%),URI (8%),Hypotension (7%),Dizziness (4%),Nausea (2%) Hydrochlorothiazide Hypotension,Anorexia,Epigastric distress,Hypokalemia,Phototoxicity,Thrombocytopenia Potentially Fatal: Hypersensitivity reactions; hemolytic anaemia; toxic epidermal necrolysis.

Interaction

Reduced excretion of lithium; effect of diuretic, natriuretic & other antihypertensive w/ NSAIDs including selective COX-2 inhibitors. Do not co-administer w/ aliskiren in patients w/ diabetes & renal impairment. Losartan: Rifampin & fluconazole. Increased serum potassium w/ K-sparing diuretics (eg spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K. Hydrochlorothiazide: Potentiate orthostatic hypotension w/ alcohol, barbiturates or narcotics. Antidiabetic drugs (oral agents, insulin), other antihypertensive drugs. Impaired absorption w/ cholestyramine & colestipol resins. Intensified electrolyte depletion w/ corticosteroids, ACTH, glycyrrhizin (liquorice). Possible decreased response to pressor amines (eg adrenaline); increased response to nondepolarizing skeletal muscle relaxants (eg tubocurarine). May interfere w/ parathyroid function test.

Buy Parten Plus from Arogga

In Bangladesh, you can get the original Parten Plus. Select your favorite one from a large collection of Medicine products. Order from App to get more offers and better experience.

What is the price of Parten Plus in Bangladesh?

The latest price of Parten Plus in Bangladesh is 5.45৳. You can buy Parten Plus at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Asked Questions (FAQ)

Is Parten Plus authentic?

Yes. Arogga sources Parten Plus products from trusted suppliers, distributors, or manufacturers. Products are verified before delivery.

Does Arogga deliver all over Bangladesh?

Arogga delivers most products across Bangladesh. However, refrigerated or cold-chain medicines are delivered only within Dhaka. Delivery of some other products may also depend on product condition, storage requirements, and delivery location.

Is Cash on Delivery (COD) available for Parten Plus?

Yes. Cash on Delivery is available for all products in eligible locations across Bangladesh. Availability may vary depending on the product and delivery location.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on product availability, delivery location, and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy..

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Parten Plus.
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CONSULT YOUR DOCTOR
Parten Plus is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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SAFE IF PRESCRIBED
Parten Plus is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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UNSAFE
Parten Plus may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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CAUTION
Parten Plus should be used with caution in patients with severe kidney disease. Dose adjustment of Parten Plus may be needed. Please consult your doctor. Use of Parten Plus is not recommended in patients with severe kidney disease.
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CAUTION
Parten Plus should be used with caution in patients with liver disease. Dose adjustment of Parten Plus may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.