Introduction
Enystin is an antifungal medication. It is used in the treatment of fungal skin infections. It kills the fungi that cause skin infections and thus treats the infection.
Enystin is for external use only. You should use it in the dose and duration as advised by your doctor. The affected area should be clean and dry before application of the ointment. You must wash your hands thoroughly before and after applying this medicine. To avoid relapse, continue the use of this medicine even if symptoms begin to clear up.
Some common side effects include skin irritation, redness or itching at the site of application. Please consult your doctor if these side effects persist for a longer duration. Avoid direct contact of the cream or ointment with your eyes. In case of direct contact, wash your eyes with water and seek immediate medical attention.
Side effects of Enystin
Common
- Application site reactions (burning, irritation, itching and redness)
How to use Enystin
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
How Enystin works
Enystin is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
What if you forget to take Enystin?
If you miss a dose of Enystin, please consult your doctor.
Indication
Fungal infections, Oropharyngeal candidiasis, Intestinal candidiasis, Vaginal candidiasis
Administration
May be taken with or without food.
Adult Dose
Oral
Oral candidiasis
Adult: As oral susp or drop : 100,000-600,000 U (1-6 ml drop) into the mouth 4 times daily. Keep in contact w/ affected area as long as possible.
Continue for 48 hr after clinical cure to prevent relapse.
Intestinal candidiasis
Adult: As tab or oral susp/drop: 500,000 or 1,000,000 U 3-4 times daily.
Prophylaxis: 1,000,000 U daily.
Vaginal
Vulvovaginal candidiasis
Adult: insert 1 vaginal tablet into vagina daily at bedtime for 14 days or longer.
Child Dose
As oral susp or drop
Infants: PO: 2 mL/dose, children 4–6 mL/dose, to coat oral mucosa q6h
As tab
Child: PO: 3–6 tabs/day tid
For prophylaxis of oral candidiasis in the newborn the suggested dose is
1 ml (100,000 U) once daily. Administration should be continued for 48 hours after clinical cure to prevent relapse.
Contraindication
Hypersensitivity.
Mode of Action
Nystatin, a polyene antifungal, binds to ergosterol in the fungal cell membrane. This binding affects the cell wall permeability allowing leakage of cellular contents.
Precaution
Immunocompromised patients. Childn. Pregnancy and lactation. Patient Counselling May damage latex contraceptives (vag).
Lactation: Not known if excreted in breast milk; use caution
Side Effect
Nausea, vomiting, diarrhoea, GI upset, oral irritation and sensitisation. Rarely, rash, urticaria, Stevens-Johnson syndrome, tachycardia, bronchospasm, facial swelling, nonspecific myalgia
Vaginal tablet: May damage latex contraceptives (e.g. diaphragms, condoms), additional contraceptive measures should be taken. Localized sensitization.
Pregnancy Category Note
Pregnancy category: C, ROUTE(S) : Mouth/Throat / PO
Pregnancy Category: A, ROUTE(S) : Vaginal