Silybin 140

Composition

Each capsule contains a standardized extract of-

• Milk thistle 175 mg equivalent to Silymarin 140 mg
• Milk thistle 87.50 mg equivalent to Silymarin 70 mg

Indications

Silymarin (Milk thistle) is indicated for the treatment and prevention of-

• Liver disease, (non-alcoholic & alcoholic)
• Liver cirrhosis, (non-alcoholic & alcoholic)
• Infectious hepatitis
• Drug-induced hepatitis
• Liver disease secondary to diabetes mellitus
• Toxicity of narcotics
• Fatty liver
• Jaundice

Therapeutic Class

Cholagogues, Cholelitholytics & Hepatic Protectors, Herbal and Nutraceuticals

Pharmacology

Silymarin, a flavonoid complex of Silybum marianum or Milk thistle, is the biologically active component. It provides hepatocellular protection through toxin blockade at the membrane level, enhances protein synthesis, antioxidant activity, anti-fibrotic activity and possible anti-inflammatory or immunomodulating effects.

Interaction

Concomitant use of silymarin and butyrophenones or phenothiazines has resulted in the reduction of lipid peroxidation.

Contraindications

Contraindicated in patient with a known hypersensitivity to silymarin.

Side Effects

Well tolerated in the recommended dose. Occasionally a mild laxative effect may observe.

Pregnancy & Lactation

No experience is available about the use of Silymarin 70 mg or 140 mg during pregnancy and lactation. Therefore, if needed Silymarin 70 mg or 140 mg should be taken with caution according to the physician’s advice.

Storage Conditions

Store in a cool & dry place, away from light & moisture. Keep out of reach of children.