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Tranbit

Name: Tranbit Tenofovir Alafenamide Tablet 25mg
Brand: Genvio Pharma Ltd.
SKU: 29115
Price: 81.81 BDT
Availability: OutOfStock
Rating: 4.8 (1 reviews)

Tablet-(25mg)

Genvio Pharma Ltd.

Generic: Tenofovir Alafenamide

1 Tablet

৳ 81.81

৳ 90

9% OFF

Alternative Brands For Tranbit

Medicine Overview of Tranbit 25mg Tablet

বাংলা

Introduction

Tranbit is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection. Tranbit should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. It is important to keep taking them until your doctor tells you it is safe to stop. Some people may experience headache as a side effect of this medicine . Please consult your doctor if it persists for a longer duration. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment. Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Tranbit

HIV infection
Chronic hepatitis B virus (HBV) infection

Side effects of Tranbit

Common

Headache

How to use Tranbit

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tranbit is to be taken empty stomach.

How Tranbit works

Tranbit is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

What if you forget to take Tranbit?

If you miss a dose of Tranbit, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

You have been prescribed Tenvir AF 25mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.

In combination with other medicines, it is used for the treatment of HIV infections.

Take it with food, as this increases the absorption of the medicine into the body.

Tenvir AF 25mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.

You may still develop infections or other illnesses associated with viral infection while taking this medication.

You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.

During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Brief Description

Indication

Chronic Hepatitis B Infection

Administration

Take with food

Adult Dose

Chronic Hepatitis B Infection Indicated for treatment of chronic hepatitis B virus (HBV) infection in adults with compensated liver disease 25 mg PO qDay with food Hepatic impairment Mild (Child-Pugh A): No dosage adjustment required Decompensated (Child-Pugh B or C) hepatic impairment: Use not recommended

Renal Dose

Renal impairment Mild, moderate, or severe: No dosage adjustment required ESRD (CrCl <15 mL/min): Use not recommended

Contraindication

Hypersensitivity

Mode of Action

Tenofovir alafenamide (AF) is a nucleotide reverse transcriptase inhibitor (NRTI) and a phosphonamidate prodrug of tenofovir Compared with tenofovir disoproxil fumarate (tenofovir DF, Viread), tenofovir AF is a more targeted form of tenofovir that has demonstrated high antiviral efficacy at a dose that is 10 times lower than tenofovir DF, as well as an improved renal and bone safety profile Tenofovir AF as a lipophilic cell-permeant compound enters primary hepatocytes by passive diffusion and by the hepatic uptake transporters OATP1B1 and OATP1B3 and is converted to tenofovir diphosphate Tenofovir diphosphate inhibits HBV replication through incorporation into viral DNA by the HBV reverse transcriptase, which results in DNA chain-termination

Precaution

Lactic acidosis and severe hepatomegaly with steatosis, including fatalities, reported with nucleoside analogs, including tenofovir disoproxil fumarate in combination with other antiretrovirals; most were reported in women; obesity and prolonged nucleoside exposure may be risks factors Discontinuation of antihepatitis B drugs may result in severe acute exacerbations of hepatitis B Owing to the risk of development of HIV-1 resistance, tenofovir AF alone is not recommended for the treatment of HIV-1 infection; test for HIV-1 before initiating treatment Lactation Unknown if distributed in human breast milk Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition

Side Effect

1-10% Headache (9%) ALT >5 x ULN (8%) Abdominal pain (7%) Fatigue (6%) Cough (6%) Glycosuria >3+ (5%) Nausea (5%) Back pain (5%)

Pregnancy Category Note

There are no human data on use in pregnant women to inform a drug-associated risks of adverse fetal developmental outcome In animal studies, no adverse developmental effects were observed when tenofovir alafenamide was administered during the period of organogenesis at exposure equal to or 51 times (rats and rabbits, respectively) the tenofovir alafenamide exposure at the recommended daily dose

Interaction

Drugs that induce P-gp result in decreased tenofovir AF absorption and plasma concentrations, which may lead to loss of therapeutic effect (eg, carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, St John’s wort) Drugs that inhibit P-gp and BCRP may increase tenofovir AF absorption and plasma concentration. Coadministration of tenofovir AF with drugs that reduce renal function or compete for active tubular secretion may increase concentrations of tenofovir and other renally eliminated drugs, and this may increase the risk of adverse reactions Some examples include acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides, high-dose or long-term NSAD use

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What is the price of Tranbit in Bangladesh?

The latest price of Tranbit in Bangladesh is 81.81৳. You can buy Tranbit at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

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Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

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Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Tranbit. Please consult your doctor.

SAFE IF PRESCRIBED

Tranbit is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

SAFE IF PRESCRIBED

Tranbit is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

UNSAFE

Tranbit may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

CAUTION

Tranbit should be used with caution in patients with kidney disease. Dose adjustment of Tranbit may be needed. Please consult your doctor.

SAFE IF PRESCRIBED

Tranbit is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tranbit may not be needed in these patients. Please consult your doctor.