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Calcefer
Renata Limited
Generic: Calcium Carbonate + Calcium Lactate Gluconate + Vitamin-C + Vitamin D3
Medicine Overview of Calcefer Tablet
বাংলা
English
Indication
Nutritional Supplement in Osteoporosis, Calcium deficiency, Rickets, Hypocalcaemia, Calcium supplement, Osteomalacia
Adult Dose
Dosage should be individualized based on the demands in age, sex and various physiological (pregnancy & lactation) & disease conditions. In general the dosage is-
Adults: 1 effervescent tablet daily
Child Dose
Dosage should be individualized based on the demands in age, sex and various physiological (pregnancy & lactation) & disease conditions. In general the dosage is-
Children above 7 years: 1 effervescent tablet daily
Children 3-7 years: Half effervescent tablet daily
Contraindication
Absolute contraindications are hypercalcaemia resulting from myeloma, bone metastases or other malignant bone disease, sarcoidosis; primary hyperparathyroidism and Vitamin-D overdosage. It is also contraindicated in severe renal failure and hypersensitivity to any of the tablet ingredients.
Mode of Action
Calcium carbonate/vitamin D3 prevents or treats negative Ca balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways. Vitamins and minerals are essential for normal metabolic functions including hematopoiesis. Vitamin D3 is a fat-soluble sterol. It is necessary for the regulation and regulation of calcium and phosphate homoeostasis and bone mineralisation. Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. Vitamin C is necessary for collagen formation and tissue...
... Show morePrecaution
Patients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully. Periodic checks of plasma Calcium levels and urinary Calcium excretion should be made in patients with mild to moderate renal failure or mild hypercalciuria. In patients with a history of renal stones urinary Calcium excretion should be measured to exclude hypercalciuria. With long-term treatment it is advisable to monitor serum and urinary Calcium levels and kidney function, and reduce or stop treatment temporarily if urinary Calcium exceeds 7.5 mmol/24 hours. Allowances should be made for Calcium and Vitamin-D supplements from other sources. Lactation: Calcium enters human...
... Show moreSide Effect
Calcium
Anorexia, Constipation, Flatulence, Nausea, Vomiting, Hypercalcemia, Hypophosphatemia, Xerostomia, Acid rebound, Milk-alkali syndrome
Vitamin D
Hypercalcemia, Muscle/bone pain, Metallic taste, Headache, Nausea, Vomiting, Dry mouth, Constipation, Arrhythmias
Interaction
Calcium Carbonate: Co-administration with thiazide diuretics or vit D may lead to milk-alkali syndrome and hypercalcaemia. Decreased absorption with corticosteroids. Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn and calcium-channel blockers. Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication. Calcium Lactate: May reduce the efficacy of calcium-channel blockers. Concurrent admin of IV calcium salt with cardiac glycosides may lead to serious adverse events. Increased risk of hypercalcaemia when used with thiazide diuretics. May reduce absorption of tetracycline, alendronate, atenolol, iron, quinolone antibiotics, sodium fluoride and zinc. Calcium Gluconate: Co-admin of high calcium doses with...
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