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Safety Advices
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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Caprolex. Please consult your doctor.
CONSULT YOUR DOCTOR
Caprolex may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Caprolex during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
It is not known whether Caprolex alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Caprolex should be used with caution in patients with kidney disease. Dose adjustment of Caprolex may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Caprolex is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Caprolex may not be needed in these patients. Please consult your doctor.
Medicine Overview of Caprolex 1gm/5ml Injection
Introduction
Caprolex is used to treat bleeding. It helps to prevent bleeding after major heart surgery and it also controls bleeding in thrombocytopenia (accompanying aplastic anemia), liver cirrhosis, urinary bleeding and some types of cancer. Caprolex works by preventing the breakdown of clots which leads to stoppage of bleeding. This injection must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy from this injection. The most common side effects may be injection site reactions such as pain, swelling and redness or pain in the muscle, bone or joint. Inform your...
... Show moreUses of Caprolex
- Bleeding
Side effects of Caprolex
Common
- Nasal congestion (stuffy nose)
- Tiredness
- Musculoskeletal (bone, muscle or joint) pain
- Injection site reactions (pain, swelling, redness)
How to use Caprolex
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Caprolex works
Caprolex prevents the breakdown of clots and stops bleeding.
What if you forget to take Caprolex?
If you miss a dose of Caprolex, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Caprolex helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
- It is given as a slow injection into a vein.
- Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
- Your doctor may monitor your vision regularly while you are taking this medicine.
- Inform your doctor if you have a history of kidney or liver disease.
Brief Description
Indication
Intravenous
Treatment and prophylaxis of haemorrhage
Adult: Initially, 4-5 g as a 2% solution over 1 hr followed by a 1 g/hr infusion continued for up to 8 hr or until bleeding has been controlled. Max: 24 g in 24 hr.
Oral
Treatment and prophylaxis of haemorrhage
Adult: Initially, 4-5 g, followed by 1-1.25 g every hr for about 8 hr or until bleeding has been controlled. Max: 24 g in 24 hr.
Patients with haemophilia undergoing dental extraction
Adult: Initially, 6 g immediately after the procedure, followed by 6 g every 6 hr for up to 10 days.
Administration
Increased risk of hypercoagulability with OC and oestrogens.
Adult Dose
Renal or cardiac disorders. Urinary tract bleeding, haematuria of upper urinary tract origin; veno-occlusive hepatic disease, skeletal myopathy, neonates. Monitor creatinine phosphokinase. Avoid admin with factor IX complex concentrates. Pregnancy and lactation.
Lactation: not known whether excreted in breast milk, use caution
Renal Dose
Aminocaproic acid inhibits the action of plasminogen activators and, to a lesser extent, it also has some antiplasmin activity.
Mode of Action
IV Administration
Initial 5 g in 250 mL over 1 hr, each subsequent gram in 50-100 mL at 1 g/hr
Rapid injection undiluted into a vein is not recommended
Continue for about 8 hr or until bleeding has been controlled
Oral
May be taken with or without food. May be taken w/ meals to prevent GI upset.
Precaution
Haemorrhage, Missed abortion, Hereditary hemorrhagic telangiectasia,Traumatic hyphema, Dental bleeding, Hemophilia A, Postoperative bleeding, Systemic hyperfibrinolysis
Side Effect
Renal impairment: Dosage reduction may be required.
Pregnancy Category Note
Oedema, headache, malaise, allergic and anaphylactic reactions, anaphylaxis, bradycardia, hypotension, peripheral ischaemia, thrombosis, abdominal pain, diarrhoea, nausea, vomiting, agranulocytosis, coagulation disorder, leukopaenia, thrombocytopaenia, increased CPK, muscle damage, myalgia, myopathy, myositis, rhabdomyolysis, confusion, convulsions, delirium, dizziness, hallucinations, intracranial hypertension, stroke, syncope, dyspnoea, nasal congestion, pulmonary embolism, pruritus, rash, tinnitus, decreased vision, watery eyes, increased BUN, dry ejaculation.
Potentially Fatal: Cardiac and hepatic damage.
Interaction
Bleeding due to disseminated intravascular coagulation. Rapid IV administration.