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Pristil
Incepta Pharmaceuticals Ltd.
Generic: Ulipristal Acetate
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pristil. Please consult your doctor.
UNSAFE
Pristil is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
SAFE IF PRESCRIBED
Pristil is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Pristil may cause side effects which could affect your ability to drive.
After taking Pristil, some women experience dizziness, drowsiness, blurred vision and/or loss of concentration. If you experience these symptoms, do not drive.
CONSULT YOUR DOCTOR
There is limited information available on the use of Pristil in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Pristil in patients with liver disease. Please consult your doctor.
Medicine Overview of Pristil 5mg Tablet
Introduction
Pristil is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus). It is used for intermittent treatment and pre-operative treatment of uterine fibroid in women of reproductive age. Pristil reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms....
... Show moreUses of Pristil
- Uterine fibroids
Side effects of Pristil
Common
- Absence of menstrual periods
- Headache
- Endometrial hyperplasia
How to use Pristil
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pristil may be taken with or without food, but it is better to take it at a fixed time.
How Pristil works
Pristil is a selective progesterone receptor modulator. It works by modifying the action of progesterone (natural female hormone). It is used either before surgery of fibroids or for intermittent (at regular intervals) treatment of fibroids. It helps reduce their size, stops or controls bleeding and increases your red blood cell count.
What if you forget to take Pristil?
If you miss a dose of Pristil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Pristil is used for the treatment of uterine fibroids and their associated symptoms, such as painful periods, heavy bleeding and pelvic pain.
- It considerably reduces or stops your menstrual bleeding within the first 10 days of treatment. Notify your doctor if you continue to have heavy bleeding despite taking Pristil.
- Your periods will usually start again within four weeks of stopping Pristil.
- Use a reliable barrier contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Pristil as it may make hormonal contraceptives (such as pills) less effective.
- Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.
Brief Description
Indication
Emergency contraception, For pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age
Administration
May be taken with or without food.
Adult Dose
Oral Emergency Contraception: One tablet taken orally as soon as possible within 120 hours (5 days) after unprotected intercourse or a known or suspected contraceptive failure. If vomiting occurs within 3 hours of Ulipristal Acetate intake, consideration should be given to repeating the dose. Uterine Fibroids: The treatment consists of 1 tablet of 5 mg to be taken orally once daily for up to 3 months. This 3-month treatment course can be repeated once. Re-treatment should start at the earliest during the second menstruation following the 1st treatment course completion. Treatments should always be started during the 1st week of...
... Show moreContraindication
Ulipristal Acetate is contraindicated for use in the case of known or suspected pregnancy.
Hypersensitivity to ulipristal acetate or to any of the excipients.
Genital bleedng or unknown aetiology or for reasons other than uterine fibroids.
Uterine, cervical, ovarian or breast cancer.
Breastfeeding.
Mode of Action
Selective progesterone receptor modulator with antagonistic and partial agonistic effects.
When taken immediately before ovulation, postpones follicular rupture.
It is thought that the primary mechanism of action for emergency contraception is inhibition or delay of ovulation; however, alterations to the endometrium that may affect implantation may also occur.
Precaution
Existing Pregnancy Not indicated for termination of an existing pregnancy. Pregnancy should be excluded before prescribing Ulipristal Acetate. Ectopic Pregnancy A history of ectopic pregnancy is not a contraindication to use of this emergency contraceptive method. Repeated Use Ulipristal Acetate is for occasional use as an emergency contraceptive. It should not replace a regular method of contraception. Repeated use of Ulipristal Acetate within the same menstrual cycle is not recommended, as safety and efficacy of repeat use within the same cycle has not been evaluated. Fertility Following Use A rapid return of fertility is likely following treatment with Ulipristal Acetate...
... Show moreSide Effect
Mood disorders; headache, dizziness; nausea, abdominal pain/discomfort, vomiting; myalgia, back pain; dysmenorrhea, pelvic pain, breast tenderness; fatigue.
Interaction
Concomitant administration of medicinal products containing progestagen is not recommended.
Also concomitant use of ulipristal acetate and potent CYP3A4 inducers (eg, rifampicin, rifabutin, carbamazepine, oxcarbazepine, phenytoin, fosphenytoin, phenobarbital, primidone, St John´s wort, efzvirenz, nevirapine, long term use of ritonavir) is not recommended.
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