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Alphalok XR 5
Opsonin Pharma Limited
Generic: Prazosin Hydrochloride
Safety Advices
বাংলা
English
UNSAFE
Alphalok XR 5 may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Alphalok XR 5 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Alphalok XR 5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Alphalok XR 5 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Alphalok XR 5 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Alphalok XR 5 may not be needed in these patients. Please consult your doctor.
Alphalok XR 5 may be started with a low dose and then increased further. Regular blood pressure monitoring is advisable for dose adjustment.
CAUTION
Alphalok XR 5 should be used with caution in patients with liver disease. Dose adjustment of Alphalok XR 5 may be needed. Please consult your doctor.
Medicine Overview of Alphalok XR 5 5 mg Tablet
Introduction
Alphalok XR 5 belongs to a class of medicines called as alpha-blocker. It is used to treat high blood pressure and lower your risk of having a heart attack or stroke. It may also be used to treat heart failure and mild enlargement of the prostate gland in men. Alphalok XR 5 may be prescribed alone or in combination with other medicines. It can be taken with or without food. The dose will depend on your condition and how you respond to the medicine. Follow the advice of your doctor on what is right for you. You need to use...
... Show moreUses of Alphalok XR 5
- Hypertension (high blood pressure)
Side effects of Alphalok XR 5
Common
- Dizziness
- Headache
- Drowsiness
- Weakness
- Low energy
- Palpitations
- Nausea
How to use Alphalok XR 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alphalok XR 5 may be taken with or without food, but it is better to take it at a fixed time.
How Alphalok XR 5 works
Alphalok XR 5 is an alpha blocker. It lowers blood pressure by relaxing blood vessels so that blood can flow more easily through the body.
What if you forget to take Alphalok XR 5?
If you miss a dose of Alphalok XR 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- You have been prescribed Minipress XL 5mg Tablet for the treatment of high blood pressure.
- It may cause sudden drop in your blood pressure, especially when you first start taking this medicine. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Do not consume alcohol while taking Minipress XL 5mg Tablet as it may enhance the blood pressure lowering effect of this medicine causing increased dizziness.
- Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
- Inform your doctor that you are taking Minipress XL 5mg Tablet if you are scheduled for a cataract surgery.
Brief Description
Indication
Hypertension, Benign prostatic hyperplasia, Raynaud's syndrome
Administration
May be taken with or without food. Starting dose is best taken w/ dinner, at least 2-3 hr before retiring. Maintenance doses may be taken w/ or w/o meals.
Adult Dose
Oral Hypertension Conventional Tablet: Adult: Initially, 0.5 mg bid or tid for 3-7 days, increased to 1 mg bid or tid for the next 3-7 days. Thereafter, the daily dose should be increased gradually as determined by the patient’s response to the blood pressure lowering effect. Most patients are likely to be maintained on a dosage regimen of Prazosin alone of up to 15 mg daily in divided doses. Max: 20 mg/day in divided doses.Dosage should be individualized depending on patient tolerance and response. Extended Release Tablet: Dosage should be individualized depending on patient tolerance and response. Adult: Initially, Prazosin...
... Show moreRenal Dose
Renal impairment: Dose reduction needed.
Contraindication
Congestive heart failure due to mechanical obstruction. Hypersensitivity. Pregnancy.
Mode of Action
Prazosin competitively blocks postsynaptic alpha1-adrenoceptors of veins and arterioles causing vasodilation, reduction in BP and total peripheral resistance usually w/o reflex tachycardia.
Precaution
Prostate cancer should be ruled out before starting therapy. Patients w/ history of micturition syncope, angina pectoris. Treatment of heart failure due to mechanical obstruction (e.g. aortic or mitral valve stenosis, pulmonary embolism and restrictive pericardial disease). During cataract surgery, Intraoperative Floppy Iris Syndrome (IFIS) may occur. Renal and hepatic impairment. Elderly. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. A low starting dose is given in the evening to lessen the risk of collapse. Hypotensive effects may be exaggerated by exercise and heat. Monitoring Parameters Monitor renal function. Careful monitoring of BP during initial...
... Show moreSide Effect
1-10%
Dizziness (10%),Drowsiness (8%),Headache (8%),Weakness (7%),Asthenia (6.5%),Nausea (5%),Palpitation (5%)
Frequency Not Defined (Selected)
Edema,Orthostatic hypotension,Syncope,Fever,Rash,Abdominal discomfort/pain,Diarrhea,Vomiting,Abnormal liver function tests,Impotence,Pancreatitis,Urinary incontinence
Potentially Fatal: Rarely, hypotension may be life-threatening.
Interaction
Hypotensive effects may be enhanced w/ diuretics and other antihypertensives. Increased risk of 1st dose hypotension w/ ?-blockers or Ca channel blockers. Concomitant admin w/ phosphodiesterase type 5 (PDE5) inhibitors (e.g. sildenafil) may result in additive hypotensive effects and symptomatic hypotension.
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