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Ciclex
Opsonin Pharma Limited
Generic: Ciclesonide
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Ciclex does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Ciclex may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Ciclex is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medicine Overview of Ciclex 50mcg/Spray Nasal Spray
Introduction
Ciclex is used to prevent the symptoms of asthma (wheezing and shortness of breath). It is a corticosteroid and is known as a "preventer". You need to have a fast-acting “reliever” as well because this medicine will not stop an asthma attack that has already started. Your doctor will tell you how often you need to use your inhaler. It is important that you take the lowest dose needed to effectively control your asthma. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be...
... Show moreUses of Ciclex
- Asthma
Side effects of Ciclex
Common
- Hoarseness of voice
- Sore throat
- Oral infections
How to use Ciclex
Rotacaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of rotahaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the rotahaler repeat the process.
How Ciclex works
Ciclex is a steroid. It prevents the cells in the lungs and breathing passages from releasing chemical messengers that cause inflammation (swelling) of the airways. This widens the airways and makes breathing easier.
Quick Tips
- Ciclex ‘dampens down’ inflammation in the lungs to provide long-term (maintenance) treatment of asthma and prevent disease progression.
- Ciclex will not work for an ongoing asthma attack. Use your rescue inhaler to control sudden difficulty in breathing.
- Learn the correct technique of using metered dose inhalers (MDI) and dry powder inhalers (DPI) to ensure that the right amount of medication reaches your lungs, and side effects are minimized.
- Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
- Take it at the same time every day to prevent asthma attacks.
- Do not open and close the cover unnecessarily as you will lose the medicine.
- Never breathe out into the mouthpiece.
- Only minuscule amounts of Ciclex may get absorbed into the bloodstream after inhalation. Hence, serious side effects such or weight gain are unlikely.
Brief Description
Indication
Asthma, seasonal allergic rhinitis, perennial allergic rhinitis
Administration
Gently shake and prime nasal spray by actuating 3 times before using for the first time or when not in use for 4 consecutive days
Adult Dose
Inhalation
Asthma
Adult: Usual dose 160 mcg once daily, preferably in the evening from a metered-dose inhaler; reduced to 80 mcg once daily for maintenance.
May increase to 160 mcg twice daily
Nasal Spray:
1 spray (50 micrograms/spray) in each nostril once a day. The maximum total daily dosage should not exceed 2 sprays in each nostril (200 micrograms/day).
Child Dose
Inhalation
Asthma
Child: >12 yr: Usual dose 160 mcg once daily, preferably in the evening from a metered-dose inhaler; reduced to 80 mcg once daily for maintenance.
May increase to 160 mcg twice daily
Nasal Spray:
1 spray (50 micrograms/spray) in each nostril once a day. The maximum total daily dosage should not exceed 2 sprays in each nostril (200 micrograms/day).
Contraindication
Not for status asthmaticus or severe acute asthma where intensive measures are needed. Ciclesonide nasal spray is contraindicated in patients with a hypersensitivity to any of its ingredients.
Mode of Action
Ciclesonide, an inhaled corticosteriod, is converted by esterases in the lungs to the active metabolite, desisobutyryl-ciclesonide, which has anti-inflammatory activity.
Precaution
Active or quiescent pulmonary TB, fungal, viral or bacterial infections, unless adequately treated. Severe hepatic impairment. Monitor height of children and adolescents on long term treatment with inhaled corticosteroids; reduce dose if growth is slow. Pregnancy, lactation. Ciclesonide nasal spray should be used with caution in patients with active or quiescent tuberculosis infection of the respiratory tract or in patients with untreated fungal, bacterial or systemic viral infections or ocular herpes simplex. Rare instances of nasal septal perforation, cataract, and glaucoma have been reported following intranasal application. Development of localized infections of the nose and pharynx with Candida albcans has...
... Show moreSide Effect
Inhalation
>10%
Headache (11%),Nasopharyngitis (11%)
1-10%
Epistaxis (4.9%),Ear pain (2.2%),Facial edema (3%),Urticaria (3%),Oral candidiasis (3%),Back pain (3%),Extremety pain (3%),Conjunctivitis (3%),Upper respiratory infection (9%),Gastroenteritis (3%),Sinusitis (3%)
Nasal spray
1-10%
Headache (3.1-6.6%),Epistaxis (2.9-6%),Nasopharyngitis (3.7%),Nasal discomfort (3.2%),Ear pain (2.2%)
Pregnancy Category Note
Pregnancy Category: C
Lactation: Not known if excreted in breast milk, use caution
Interaction
Increased ciclesonide concentrations with concomitant ketoconazole, itraconazole, ritonavir, nelfinavir or other potent CYP3A4 inhibitors.
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