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Deflaxen
Everest Pharmaceuticals Ltd.
Generic: Deflazacort
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Deflaxen.
CONSULT YOUR DOCTOR
Deflaxen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Deflaxen is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
SAFE
Deflaxen does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Deflaxen is safe to use in patients with kidney disease. No dose adjustment of Deflaxen is recommended.
However, inform your doctor if you have any kidney disease.
CAUTION
Deflaxen should be used with caution in patients with severe liver disease. Dose adjustment of Deflaxen may be needed. Please consult your doctor.
Limited information is available on the use of Deflaxen in these patients.
Medicine Overview of Deflaxen 6mg/5ml Powder for Suspension
Introduction
Deflaxen belongs to a group of medicines called steroids. It is used for treatment of various diseases and conditions such as allergic conditions, asthma, cancer, rheumatic disorder, and skin and eye disorders. Deflaxen works by inhibiting the release of substances that cause swelling or by changing how the immune system works. It can be taken in an empty stomach or after food. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. Taking this medicine can cause few common side...
... Show moreUses of Deflaxen
- Severe allergic reactions
- Allergic conditions
- Asthma
- Cancer
- Rheumatic disorder
- Skin disorders
- Eye disorders
Side effects of Deflaxen
Common
- Increased appetite
- Frequent urge to urinate
- Facial swelling
- Abnormal hair growth
- Cushing syndrome
- Cough
How to use Deflaxen
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Deflaxen may be taken with or without food, but it is better to take it at a fixed time.
How Deflaxen works
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Quick Tips
- Deflaxen helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
- Do not use it more often or for longer than advised by your doctor.
- Take it with food to avoid an upset stomach.
- Deflaxen can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
- Side effects such as mood changes or stomach problems can happen when you start taking Deflaxen. Inform your doctor if this bothers you.
- Do not stop taking Deflaxen suddenly without talking to your doctor first as it may worsen your symptoms.
Brief Description
Indication
Allergic and inflammatory disorders
Adult Dose
Oral
Allergic and inflammatory disorders
Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day.
Hepatic impairment: Dose reductions may be needed.
Child Dose
Oral
Allergic and inflammatory disorders
Child: 0.25-1.5 mg/kg/day given on alternate days.
Contraindication
Systemic infection; live virus vaccines in those receiving immunosuppressive doses.
Mode of Action
Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.
Precaution
Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation.
Side Effect
GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism.
Pregnancy Category Note
Pregnancy
Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
Infants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism
Lactation
Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects
Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition
Interaction
Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, ?-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, ?2 sympathomimetics, theophylline, vaccines.
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