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Nilonix 150

Capsule-(200mg)
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Beacon Pharmaceuticals PLC

Generic: Nilotinib

1 Capsule
৳ 590.85
৳ 650
9% OFF
Alternative Brands For Nilonix 150

Medicine Overview of Nilonix 150 200mg Capsule

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Introduction

Nilonix 150 is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects. Nilonix 150 should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Headache, nausea, abdominal pain, and rash are very common side effects of this medicine. If you experience severe diarrhea, consult with your doctor or drink plenty of fluids while on treatment. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels and blood sugar or fat level in the body. Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Nilonix 150

  • Blood cancer (Chronic myeloid leukaemia)

Side effects of Nilonix 150

Common
  • Headache
  • Nausea
  • Abdominal pain
  • Rash
  • Itching
  • Hair loss
  • Muscle pain
  • Fatigue

How to use Nilonix 150

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Nilonix 150 is to be taken empty stomach.

How Nilonix 150 works

Nilonix 150 is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

What if you forget to take Nilonix 150?

If you miss a dose of Nilonix 150, skip it and continue with your normal schedule. Do not double the dose.

Quick Tips

  • Nilonix 150 is used for the treatment of thyroid cancer.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Brief Description

Indication

Chronic myelogenous leukaemia

Administration

Should be taken on an empty stomach. Avoid food at least 2 hr before & at least 1 hr after a dose. Swallow whole, do not chew/crush. Avoid grapefruit products.

Adult Dose

Oral Chronic Myeloid Leukemia (CML), Newly Diagnosed Indicated for initial treatment of newly diagnosed Philadelphia chromosome positive chronic phase chronic myeloid leukemia (Ph+ CP-CML) 300 mg PO q12hr Chronic Myeloid Leukemia (CML), Resistant/Intolerant Indicated for treatment of chronic phase and accelerated pase Ph+ CML in patients resistant to or intolerant to prior therapy that included imatinib 400 mg PO q12hr Hepatic Impairment Newly diagnosed Ph+ CML (chronic phase at 300 mg BID) Mild, moderate, or severe hepatic impairment: Start initial dose at 200 mg BID; if tolerated, may increase to 300 mg BID Resistant or intolerant Ph+ CML (chronic phase or accelerated phase at 400 mg BID) Mild or moderate hepatic impairment: Start initial dose at 300 mg BID; if tolerated, may increase to 400 mg BID Severe hepatic impairment: Start initial dose at 200 mg BID; if tolerated, may increase to 300 mg BID, and then 400 mg BID

Child Dose

<18 years old: Not recommended

Contraindication

Patients with hypokalaemia, hypomagnaesemia or long QT syndrome. Pregnancy.

Mode of Action

Nilotinib is a potent inhibitor of BCR-ABL tyrosine kinase. It binds to and stabilises the inactive conformation of the kinase domain of Abl protein.

Precaution

Patient w/ history of pancreatitis, w/ total gastrectomy. Hepatic impairment. Maintain adequate hydration and correct uric acid levels, hypomagnesaemia, hypokalaemia and other electrolyte imbalances prior to therapy. Pregnancy and lactation. Monitoring Parameters Monitor ECG, CBC, hepatic function, serum lipase regularly. Monitor electrolyte periodically during therapy. Lactation: not known if excreted in breast milk; do not nurse

Side Effect

>10% Rash (33%),Headache (31%),Nausea (31%),Pruritus (29%),Fatigue (28%),Pyrexia (24%),Diarrhea (22%),Constipation (21%),Vomiting (21%),Arthralgia (18%),Cough (17%),Extremity pain (16%),Asthenia (14%),Muscle spasms (14%),Myalgia (14%),Abdominal pain (13%),Bone pain (13%),Back pain (12%),Dyspnea (11%),Nasopharyngitis (11%),Peripheral edema (11%) 1-10% (selected) Dizziness,Insomnia,Paresthesia,QT interval prolongation,HTN,Palpitations,QT interval prolongation,Hyperglycemia,Hyperkalemia,Hypomagnesemia,Neutropenia,Pancytopenia <1% Peripheral arterial occlusive disease,Tumor lysis syndrome,Aortic valve sclerosis,Abscess,Amnesia,Dehydration Potentially Fatal: QT prolongation and sudden deaths.

Interaction

Drugs that inhibit gastric acid secretion (e.g. PPIs) may reduce solubility and bioavailability of nilotinib. Potentially Fatal: Concomitant use w/ potent CYP3A4 inhibitors or antiarrhythmics (e.g. amiodarone, disopyramide, quinidine, sotalol, ketoconazole, clarithromycin, atazanavir) and other QT prolonging drugs (e.g. chloroquine, haloperidol, methadone, moxifloxacin, pimozide) may increase nilotinib serum levels and/or increase the risk of QT prolongation. Concomitant use w/ potent CYP3A4 inducers (e.g. rifampcin, phenobarbital, carbamazepine, phenytoin) may decrease nilotinib serum levels.

Buy Nilonix 150 from Arogga

In Bangladesh, you can get the original Nilonix 150. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Nilonix 150 in Bangladesh?

The latest price of Nilonix 150 in Bangladesh is 590.85৳. You can buy Nilonix 150 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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SAFE
Consuming alcohol with Nilonix 150 does not cause any harmful side effects.
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CONSULT YOUR DOCTOR
Nilonix 150 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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UNSAFE
Nilonix 150 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
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UNSAFE
Nilonix 150 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
Nilonix 150 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nilonix 150 may not be needed in these patients. Please consult your doctor.
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CAUTION
Nilonix 150 should be used with caution in patients with liver disease. Dose adjustment of Nilonix 150 may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.