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Flixocort 125
Healthcare Pharmaceuticals Ltd.
Generic: Fluticasone Propionate Inhalation
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
Flixocort 125 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Flixocort 125 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medicine Overview of Flixocort 125 125mcg/metered dose Inhaler
Introduction
Flixocort 125 is a steroid. It relieves the symptoms of allergic rhinitis such as runny nose, sneezing and sinus discomfort. It works by blocking the production of certain chemical messengers that cause inlammation (swelling) and allergies, thus relieving the discomfort and irritation in your nose. You should always use Flixocort 125 as advised by your doctor. To get the full benefit of the medicine you should take it regularly. Normally, you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other and then sniff hard to make sure it reaches deep...
... Show moreUses of Flixocort 125
- Sneezing and runny nose due to allergies
Side effects of Flixocort 125
Common
- Nasal irritation
How to use Flixocort 125
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.
How Flixocort 125 works
Flixocort 125 is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.
Quick Tips
- The right way to use the nasal spray:
- Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.
- Do not share the bottle with anyone else so that you do not spread germs.
- Flixocort 125 should be avoided in patients with recent nasal ulcers, nasal surgery, or nasal trauma.
Brief Description
Indication
Inhalation as, Asthma prophylaxis, Nebuliser suspension as prophylactic management in severe asthma (patients requiring high dose inhaled or oral corticosteroid therapy), Treatment of mild to moderate acute exacerbation of asthma.
Administration
Prime inhaler (4 actuations into air) before first use and after prolonged (>7 days) idleness
Valve holding chamber and face mask may be used for younger patients
Adult Dose
Inhalation
Asthma prophylaxis
Adult: As fluticasone propionate powd or aerosol inhaler: 100 mcg bid in mild asthma, up to 500-1,000 mcg bid in severe cases.
Nebuliser suspension
Adults and adolescents over 16 years (prophylactic management in severe asthma):
0.5-2 mg twice daily. The recommended initial dose is 2mg twice daily. The dosage should then be adjusted until control is achieved or reduced to the minimum effective dose according to the individual response.
Child Dose
Inhalation
Asthma prophylaxis
Child: 4-16 yr As fluticasone propionate powd or aerosol inhaler: 50-100 mcg bid, increased to 200 mcg bid if necessary.
<4 years: Safety and efficacy not established
Nebuliser suspension
Children and adolescents 4 to 16 years of age (treatment of acute exacerbations of asthma): 1mg twice daily.
Contraindication
Hypersensitivity to drug, components or milk proteins, which may result in anaphylaxis, angioedema, rash, and urticaria.
Primary treatment of status asthmaticus, acute bronchospasm.
Mode of Action
Fluticasone utilises a fluorocarbothioate ester linkage at the 17 carbon position. It has potent vasoconstrictive and anti-inflammatory activity, but weak hypothalamic-pituitary-adrenal (HPA) inhibitory effect when applied topically. Fluticasone shown to exhibit anti-inflammatory effect on neutrophils, eosinophils, macrophages, mast cells, lymphocytes, and mediators (histamine, leukotrienes, cytokines, eicosanoids)
Precaution
Respiratory tract tuberculosis, untreated fungal or bacterial infections, viral or parasitic infections, ocular herpes simplex; care must be taken to avoid exposure Nasal septum perforation, epistaxis, wheezing Cataracts, glaucoma, increased intraocular pressure may occur; monitor for glaucoma and cataracts Risk of more serious or fatal course of chickenpox or measles in susceptible patients (eg, unvaccinated or immunologically unexposed individuals); care must be taken to avoid exposure Hypercorticism and adrenal suppression may occur with high dosages or at regular dosage in susceptible individuals; if such changes occur, taper withdrawal gradually May decrease growth velocity in children; monitor growth of pediatric patients...
... Show moreSide Effect
>10% Oral candidiasis (<31%),Throat irritation (3-22%),Upper respiratory tract infection (16-18%),Fatigue or malaise (16%),Nasal congestion (16%),Rhinitis (<13%),Musculoskeletal pain (2-12%),Headache (5-11%) 1-10% Nasal congestion (8%),Sinusitis or sinus infection (4-7%),Cough (4-6%),Bronchitis (2-6%),Hoarseness or dysphonia (2-6%),Allergic rhinitis (5%),Nasal discharge (5%),Upper respiratory inflammation (2-5%),Muscle injury (<5%),Gastrointestinal (GI) discomfort or pain (1-4%) Frequency Not Defined Hypersensitivity reactions (including anaphylaxis, angioedema, rash, urticaria) Respiratory: Rhinitis, rhinorrhea or postnasal drip, nasal sinus disorders, laryngitis GI: Diarrhea, loss of taste, viral infections, dyspeptic symptoms, discomfort, pain, hyposalivation Muscular: Musculoskeletal pain, stiffness, tightness, rigidity, injuries, soreness Other: Dizziness, migraine, fever, viral infection, pain, chest symptoms, viral skin infections, soft tissue...
... Show morePregnancy Category Note
Pregnancy There are no randomized clinical studies in pregnant women; in women with poorly or moderately controlled asthma, there is increased risk of several perinatal adverse outcomes (eg, pre-eclampsia in the mother, prematurity, low birth weight, and small for gestational age in the neonate;) Pregnant women with asthma should be closely monitored and medication adjusted as necessary to maintain optimal asthma control Lactation Fluticasone propionate concentrations in plasma after inhaled therapeutic doses are low; concentrations in human breast milk are likely to be correspondingly low Developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need...
... Show moreব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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Flixocort 125
Healthcare Pharmaceuticals Ltd.