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Citapram 20
General Pharmaceuticals Ltd.
Generic: Citalopram Hydrobromide
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Citapram 20.
CONSULT YOUR DOCTOR
Citapram 20 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Citapram 20 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for behavioral side effects such as sleepiness or fussiness.
UNSAFE
Citapram 20 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Citapram 20 should be used with caution in patients with severe kidney disease. Dose adjustment of Citapram 20 may be needed. Please consult your doctor.
Limited information is available on the use of Citapram 20 in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
CAUTION
Citapram 20 should be used with caution in patients with liver disease. Dose adjustment of Citapram 20 may be needed. Please consult your doctor.
Medicine Overview of Citapram 20mg Tablet
Introduction
Citapram 20 is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed to treat depression, where it helps to make you feel better and prevent new episodes of depression. This medicine is also used to treat panic disorder. Citapram 20 can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or...
... Show moreUses of Citapram 20
- Depression
- Panic disorder
Side effects of Citapram 20
Common
- Erectile dysfunction
- Insomnia (difficulty in sleeping)
- Low sexual desire
- Nausea
- Restlessness
- Upset stomach
- Vomiting
How to use Citapram 20
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Citapram 20 may be taken with or without food, but it is better to take it at a fixed time.
How Citapram 20 works
Citapram 20 is one of a group of antidepressants called selective serotonin reuptake inhibitors, or SSRIs. It is thought to be work by enhancing the level of mood-enhancing neurotransmitters called serotonin in the brain. This may help you to improve your energy level and feelings of well-being.
What if you forget to take Citapram 20?
If you miss a dose of Citapram 20, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- It can take up to 8 to 12 weeks to see the medicine full effects on your mood.
- Take it with food to avoid stomach upset.
- It causes less drowsiness as compared to other antidepressant medications.
- Don't drive or do anything requiring concentration until you know how Citapram 20 affects you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
- Do not stop taking the medication suddenly without talking to your doctor.
Brief Description
Indication
Depressive illness, Bipolar disorder, Panic disorder, Substance abuse disorders, Alcohol dependence, Anxiety disorders including obsessive-compulsive disorder and social phobia, Post-traumatic stress disorder, Premenstrual syndrome, Idiopathic Parkinson's disease and Eating disorder.
Administration
May be taken with or without food.
Adult Dose
Oral
Depression; Depressive phase of bipolar disorder
Adult: Initially, 20 mg/day, increased to max 40 mg/day after at least 1 wk.
Elderly: 10 mg/day. Max: 20 mg/day.
Hepatic impairment: Mild to moderate: 10 mg/day for the 1st 2 wk. Max: 20 mg/day.
Panic disorder with or without agoraphobia
Adult: Initially, 10 mg/day, increased to 20 mg/day after 1 wk.
Elderly: 10 mg/day. Max: 20 mg/day.
Hepatic impairment: Mild to moderate: 10 mg/day for the 1st 2 wk. Max: 20 mg/day.
Child Dose
Child: Contraindicated.
Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Hypersensitivity, concomitant admin with MAOIs or within 14 days of discontinuing MAOI treatment; children and adolescents <18 yr; treatment of depressive illness; lactation.
Mode of Action
Citalopram is bicyclic phthalane derivative and a selective serotonin re-uptake inhibitor, w/ little or no effect on noradrenaline, dopamine and GABA re-uptake. The inhibitory activity explains the antidepressant property of citalopram. It has no or very low affinity for 5-HT1AA, 5-HT2A, D1 and D2 receptors, alpha 1, alpha2, beta-adrenergic, histamine H1, muscarinic, cholinergic, benzodiazepine and opioid receptors.
Precaution
Caution should be taken in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders, hepatic and renal impairment. Abrupt withdrawal of Citalopram should be avoided. Gradual discontinuation of treatment if patient enters into manic phase; pregnancy. Increased risk of hyponatraemia and SIADH. May reduce convulsant threshold thus, citalopram should be used with care in epileptic patients.
Lactation: Excreted in breast milk; use caution
Side Effect
>10%
Dry mouth (20%),Nausea (21%),Somnolence (18%),Insomnia (15%),Xerostomia (20%),Increased sweating (11%)
1-10%
Tremor (8%),Diarrhea (8%),Ejaculation disorder (6%),Rhinitis (5%),Upper respiratory infection (5%),Dyspepsia (5%),Fatigue (5%),Vomiting (4%),Anxiety (4%),Anorexia (4%),Abdominal pain (3%),Agitation (3%),Impotence (3%),Sinusitis (3%),Dysmenorrhea (3%),Decreased libido (2%),Yawning (2%),Arthralgia (2%),Myalgia (2%),Amenorrhea (>1%),Confusion (>1%),Cough (>1%),Flatulence (>1%),Increased saliva (>1%),Migraine (>1%),Orthostatic hypotension (>1%),Paresthesia (>1%),Polyuria (>1%),Pruritus (>1%),Rash (>1%),Tachycardia (>1%),Weight change (>1%)
Potentially Fatal: Increased risk of suicidal thinking and behaviour especially in child and adolescents. Monitor closely for signs of clinical worsening, suicidality or unusual changes in behaviour.
Pregnancy Category Note
Pregnancy
Pregnancy category: C
Use late in the third trimester associated with complications in newborns and may require prolonged hospitalization, respiratory support, and tube feeding
Lactation
Excreted in breast milk; use caution
Interaction
May increase anticoagulant effect w/ drugs affecting haemostatis (e.g. warfarin). Increased risk of hypomania w/ sibutramine. Increased lowering seizure threshold w/ TCAs and other SSRIs.
Potentially Fatal: Increased risk of severe adverse effects (e.g. serotonin syndrome) w/ MAOI. QT interval prolongation w/ subsequent risk of torsade de pointes w/ QT-prolonging drugs (e.g. pimozide, quinidine, procainamide, chlorpromazine, thioridazine, amiodarone, sotalol, moxifloxacin, pentamidine, levomethadyl, methadone).
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