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Aggreno
Ziska Pharmaceuticals Ltd.
Generic: Aspirin + Dipyridamole
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Aggreno.
CONSULT YOUR DOCTOR
Aggreno is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Aggreno is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Aggreno may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Aggreno is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Aggreno may not be needed in these patients. Please consult your doctor.
SAFE IF PRESCRIBED
Aggreno is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aggreno may not be needed in these patients. Please consult your doctor.
Medicine Overview of Aggreno 25mg+200mg Capsule
Introduction
Aggreno is a combination of two medicines that mainly prevent clot formation in the blood vessels. It also helps to prevent another stroke in patients with a history of previous stroke or mini-stroke (transient ischaemic attack). Aggreno should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking...
... Show moreUses of Aggreno
- Blood clots
Side effects of Aggreno
Common
- Increased bleeding tendency
- Diarrhea
- Indigestion
- Vomiting
- Headache
How to use Aggreno
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aggreno is to be taken with food.
How Aggreno works
Aggreno is a combination of two antiplatelet medicines: Aspirin and Dipyridamole which prevent stroke following an initial first stroke (transient ischaemic attack). It works by preventing platelets from sticking together which decreases the formation of harmful blood clots.
Quick Tips
- You have been prescribed Arreno Capsule ER for preventing blood clots that cause a stroke.
- It can be taken with or without food.
- Arreno Capsule ER increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Notify your doctor if you experience stomach pain, nausea or vomiting that doesn't go away.
- Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Brief Description
Indication
Secondary prophylaxis of transient ischemic attack (TIA), cerebrovascular accident (CVA)
Administration
May be taken with or without food. Swallow whole, do not chew/crush.
Adult Dose
Stroke
Secondary prophylaxis of transient ischemic attack (TIA) or cerebrovascular accident (CVA)
Adult:
1 capsule bid
Hepatic impairment: Avoid in severe impairment.
Renal Dose
Renal impairment:
CrCl (ml/min) <10: Avoid.
Contraindication
Hypersensitivity, allergy to NSAIDs. Bleeding disorders (factor VII or IX deficiencies). Patients with asthma, rhinitis or nasal polyps. Children <16 yr with viral infections.
Mode of Action
Aspirin inhibits platelet aggregation by irreversible inhibition of platelet cyclooxygenase and thus the formation of thromboxane A2 in the platelets.
Dipyridamole inhibits platelet aggregation by preventing the uptake of adenosine into platelets, endothelial cells and RBCs. The combination results in additive antiplatelet effects.
Precaution
Unstable angina, recent MI, subaortic stenosis, severe coronary artery disease, hypotension, history of peptic ulcer disease. Monitor for signs of ulceration or bleeding, even in the absence of previous GI symptoms. Patients with inherited or acquired bleeding disorders. Admin of dipyridamole may cause increase in hepatic enzymes and hepatic failure. Avoid aspirin in patients with severe renal failure (CrCl <10 mL/minute). Discontinue if tinnitus or impaired hearing occurs. Dose of aspirin in this preparation is insufficient to prevent MI. Pregnancy, lactation.
Lactation: Drug enters breast milk; use with caution
Side Effect
>10%
Headache (10-39%),Dyspepsia (4-18%),Abdominal pain (4-18%),Nausea (6-16%),Diarrhea (13%)
1-10%
Vomiting (3-8%),Pain (6%),Fatigue (6%),Arthralgia (5%),Back pain (5%),Hemorrhage, nonspecific (3%),Accidental injury (3%),Epistaxis (3%),Amnesia (3%),Arthritis (2%),Melena (2%),Asthenia (2%),Convulsions (2%),Neoplasm, nonspecific (2%),Anemia (2%),Rectal hemorrhage (2%),Malaise (2%),Cardiac failure (2%),Coughing (2%),Purpura (1%),GI hemorrhage (1%),Anorexia (1%),Somnolence (1%)
,Myalgia (1%),Arthrosis (1%),Confusion (1%),Hemorrhoids (1%),Syncope (1%),Upper respiratory tract infection (1%)
Pregnancy Category Note
Pregnancy Available data from published studies and postmarketing experience with use during pregnancy have not identified clear association between drug use and major birth defects, miscarriage, or adverse maternal or fetal outcomes drug combination contains low-dose aspirin which is an NSAID Increases risk for bleeding; maternal use of high-dose aspirin can result in excessive blood loss at delivery, prolonged gestation, prolonged labor, intracranial hemorrhage in premature infants, low birth weight, stillbirth, and neonatal death Lactation Based on data from a clinical lactation study in breastfeeding women taking low-dose aspirin, the metabolite salicylic acid is present in human milk in low...
... Show moreInteraction
Aspirin: May reduce hypotensive and hyponatraemic effects of ACE inhibitors; may increase serum levels and toxicity of acetazolamide; increases anticoagulant effect of heparin, thus increasing bleeding risk; may reduce hypotensive effect of β-blockers; may reduce efficacy of diuretics in patients with underlying renal or CV disease; salicylate may inhibit renal clearance of methotrexate, thus increasing the risk of bone marrow toxicity; increased risk of bleeding or reduced renal function when used with NSAIDs; increased risk of hypoglycaemia when used with oral hypoglycaemic drugs; salicylate antagonises the uricosuric effect of uricosuric agents; may increase adverse effect of alendronate. Dipyridamole: May antagonise...
... Show moreব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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