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Epicure

Oral Solution-(10mg/ml)
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Incepta Pharmaceuticals Ltd.

Generic: Brivaracetam

1 x 50ml bot
৳ 540
৳ 600
10% OFF
Alternative Brands For Epicure

Medicine Overview of Epicure 10mg/ml Oral Solution

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Introduction

Epicure is an anti-epileptic medicine used to treat seizures (fits) in epilepsy. It can be used alone or along with other medicines. It helps to prevent seizures for as long as you continue to take it. Epicure suppresses the abnormal electrical activity in the brain. You can take it regularly with or without food but try to take it at the same time each day to get the most benefit. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your seizures. It may be increased gradually. It is generally advised as a long-term treatment. You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. Do not stop taking this medicine unless your doctor tells you to. This is because stopping the medicine suddenly could make your seizures worse. Some common side effects of this medicine include dizziness, headache, irritation, nausea, and vomiting. You may also experience behavioral changes, aggressive behavior, irritation, agitation, etc. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most of these side effects do not need medical attention, but some of them can be serious. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse. Before taking it, you should tell your doctor if you have liver or kidney-related problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. Breastfeeding mothers should also consult their doctor before taking this medicine.

Uses of Epicure

  • Epilepsy/Seizures

Side effects of Epicure

Common
  • Dizziness
  • Fatigue
  • Nausea
  • Sleepiness
  • Vomiting
  • Constipation
  • Irritation

How to use Epicure

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epicure may be taken with or without food, but it is better to take it at a fixed time.

How Epicure works

Epicure is an antiepileptic medication. It works by attaching itself to specific sites (SV2A) on the surfaces of nerve cells. This suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.

Quick Tips

  • Epicure should be taken regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
  • It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
  • Inform your doctor if you have a history of liver disease, kidney disease or drug abuse.
  • Do not stop using Epicure without talking to your doctor, even if you feel better.

Brief Description

Indication

Partial-Onset Seizures, Adjunctive therapy in treating partial-onset seizures w/ or w/o secondary generalisation in adults & adolescents ≥16 yr w/ epilepsy.

Adult Dose

Partial-Onset Seizures Indicated for partial-onset seizures 50 mg PO/IV q12hr initially; based on individual patient tolerability and therapeutic response, adjust dose between to 25-100 mg PO/IV BID (50-200 mg/day) Injection may be used for patients when oral administration is temporarily not feasible; clinical study experience with injection is limited to 4 consecutive days of treatment Hepatic impairment All stages: Decrease starting dose to 25 mg BID and do not exceed 75 mg BID (150 mg/day)

Child Dose

Partial Onset Seizures Tablets or oral solution Indicated for partial-onset seizures in children and adolescents ?4 years <4 years: Safety and efficacy not established 4 to <16 years 11 to <20 kg: 0.5-1.25 mg/kg PO BID (1-2.5 mg/kg/day) initially; based on individual patient tolerability and therapeutic response, adjust dose between to 0.5-2.5 mg/kg PO BID (1-5 mg/kg/day) 20 to <50 kg: 0.5-1 mg/kg PO BID (1-2 mg/kg/day) initially; based on individual patient tolerability and therapeutic response, adjust dose between to 0.5-2 mg/kg PO BID (1-4 mg/kg/day) ?50 kg: 25-50 mg PO BID (50-100 mg/day) initially; based on individual patient tolerability and therapeutic response, adjust dose between to 25-100 mg PO BID (50-200 mg/day) >16 years 50 mg PO BID (100 mg/day) initially; based on individual patient tolerability and therapeutic response, adjust dose between to 25-100 mg PO BID (50-200 mg/day) Injection Indicated for partial-onset seizures in adolescents ?16 years with epilepsy Injection may be used for patients when oral administration is temporarily not feasible <16 years: Safety and efficacy not established >16 years: 50 mg IV q12hr initially; based on individual patient tolerability and therapeutic response, adjust dose between to 25-100 mg IV BID (50-200 mg/day) Clinical study experience with injection is limited to 4 consecutive days of treatment

Renal Dose

Renal impairment Mild-to-moderate: No dose adjustment required ESRD undergoing dialysis: Not studied

Contraindication

Hypersensitivity; bronchospasms and angioedema have occurred

Mode of Action

Exact mechanism unknown Displays a high and selective affinity for synaptic vesicle protein 2A (SV2A) in the brain, which may contribute to the anticonvulsant effect

Precaution

Monitor patients for signs of suicidal ideation & behaviours. Minor or moderate influence on the ability to drive & use machines. Hepatic impairment. Not recommended in end-stage renal disease patients undergoing dialysis. Women of childbearing potential. Pregnancy & lactation. Elderly ≥65 yr. Childn <16 yr. FC tab: Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Oral soln: Rare hereditary problems of fructose intolerance. Contains methyl parahydroxybenzoate (E218). Oral soln & vial: Patients on controlled Na diet.

Side Effect

>10% Somnolence and sedation (16%) Dizziness (12%) 1-10% Fatigue (9%) Nausea and vomiting (5%) Cerebellar coordination and balance disturbances (3%) Irritability (3%) Constipation (2%)

Pregnancy Category Note

Pregnancy No adequate and well-controlled studies in pregnant women In animal studies, brivaracetam produced evidence of developmental toxicity at plasma exposures greater than clinical exposure Lactation Unknown if distributed in human breast milk Studies in rats have shown excretion in milk Because many drugs are excreted into human milk, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother

Interaction

Doubled effect of alcohol on psychomotor function, attention & memory. Possible increase in plasma conc w/ strong CYP2C19 inhibitors (eg, fluconazole, fluvoxamine). Decreased plasma conc w/ strong enzyme inducers (eg, rifampicin; carbamazepine, phenobarb, phenytoin; St. John's wort). May increase plasma conc of CYP2C19-metabolised products (eg, lansoprazole, omeprazole, diazepam); OAT3-transported medicinal products. May decrease plasma conc of CYP2B6-metabolised products (eg, efavirenz). Increased conc of carbamazepine epoxide.

Buy Epicure from Arogga

In Bangladesh, you can get the original Epicure. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Epicure in Bangladesh?

The latest price of Epicure in Bangladesh is 540৳. You can buy Epicure at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Epicure.
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CONSULT YOUR DOCTOR
Epicure may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Information regarding the use of Epicure during breastfeeding is not available. Please consult your doctor.
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UNSAFE
Epicure may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
Epicure is safe to use in patients with kidney disease. No dose adjustment of Epicure is recommended. It is not recommended in end-stage renal disease due to a lack of clinical trial data.
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CAUTION
Epicure should be used with caution in patients with liver disease. Dose adjustment of Epicure may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.