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Fosfomax 4
Square Pharmaceuticals PLC.
Generic: Fosfomycin
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Fosfomax 4 does not cause any harmful side effects.
SAFE IF PRESCRIBED
Fosfomax 4 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Fosfomax 4 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Fosfomax 4 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Fosfomax 4 should be used with caution in patients with kidney disease. Dose adjustment of Fosfomax 4 may be needed. Please consult your doctor.
Use of Fosfomax 4 is not recommended in patients with severe kidney disease.
CONSULT YOUR DOCTOR
There is limited information available on the use of Fosfomax 4 in patients with liver disease. Please consult your doctor.
Medicine Overview of Fosfomax 4 4gm/vial Injection
Introduction
Fosfomax 4 belongs to a group of medicines known as antibiotics. It works by killing bacteria, which can cause infections. This medicine is used to treat or prevent infections of the urinary tract. It helps to improve your symptoms and cure the infection. Fosfomax 4 should be taken on an empty stomach, preferably before bedtime, after emptying the bladder. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed...
... Show moreUses of Fosfomax 4
- Bacterial infections of urinary tract
Side effects of Fosfomax 4
Common
- Headache
- Dizziness
- Vaginal inflammation
How to use Fosfomax 4
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Fosfomax 4 is to be taken empty stomach.
How Fosfomax 4 works
Fosfomax 4 is an antibiotic. It kills the bacteria in the urinary tract by preventing them from forming their own protective covering. It also reduces bacterial attachment to cells lining the bladder. This helps treat or prevent uncomplicated infections of the bladder.
Quick Tips
- Fosfomax 4 is used to treat and prevent bacterial infections of the urinary tract.
- Dissolve it in a glass of water and drink immediately, preferably at bedtime, 2 hours after meals (after emptying the bladder).
- Avoid alcohol and caffeinated drinks, and drink plenty of water while taking Fosfomax 4.
- Diarrhea is a common side effect. Inform your doctor if it does not get better or if you see blood in stools.
- Fosfomax 4 may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
- Symptoms should get better in 2 to 3 days of the single dose treatment. Inform your doctor if you don't feel better after 2 to 3 days.
Brief Description
Indication
Uncomplicated urinary tract infections (acute cystitis), Prostatitis
Administration
Reconstitution: Oral powd: Dissolve the contents of a single-dose sachet containing 3 g of the drug in 90-120 ml (half cup) of water of water and stir to dissolve. Do not use hot water. This should be taken immediately after dissolving in water. Do not use hot water.
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals.
Adult Dose
Oral
Urinary Tract Infection (Acute Cystitis)
Acute cystitis caused by E. coli, E. faecalis
Women >18 years: 1 sachet (3 g) PO once
Males >18 years: 1 sachet (3 g) every 2-3 days for 3 doses
Prostatitis
3 g PO every 3 days for 21 days
Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Hypersensitivity to fosfomycin.
Mode of Action
Fosfomycin is a phosphoenolpyruvate (PEP) analogue that irreversibly inhibits enolpyruvate transferase (MurA), which prevents peptidoglycan biosynthesis at an earlier site compared to β-lactams with no cross-resistance with other agents. Thus, it inhibits bacterial cell wall biogenesis & shows bactericidal effects.
Precaution
Patient w/ cardiac insufficiency, HTN, hyperaldosteronism, hypernatraemia or pulmonary oedema. Renal impairment (IV). Pregnancy and lactation. Patient Counseling Certain adverse effects may occur which may impair ability to drive or operate machinery. Monitoring Parameters Monitor serum electrolyte levels and water balance; signs and symptoms of UTI. Do not use more than one single dose to treat a single episode of acute cystitis. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. Lactation:...
... Show moreSide Effect
1-10%
Anorexia,Diarrhea,Epigastric,Discomfort,Headache,Nausea,Rash,Vomiting
<1%
Dizziness,Drowsiness,Fatigue,Pruritus
Potentially Fatal: Anaphylactic shock, antibiotic-associated colitis and pseudomembranous colitis.
Pregnancy Category Note
Pregnancy Category: B
Lactation: excreted in breast milk; not recommended
Interaction
Additive or synergistic effect w/ β-lactam antibiotics (e.g. penicillin, ampicillin, cefazolin, carbapenems) and anti-staphylococcal agents (e.g. linezolid, quinupristin/dalfopristin, moxifloxacin). Reduced serum levels w/ drugs which increase GI motility (e.g. metoclopramide).
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