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Covan

Injection-(500mg)
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Renata Limited

Generic: Vancomycin

1 Injection
৳ 225
৳ 250
10% OFF
Alternative Brands For Covan

Medicine Overview of Covan 500mg Injection

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Introduction

Covan is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood and others. Covan is also used for the prevention of infection in some high-risk patients undergoing surgical procedures. It works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is administered slowly by a drip (infusion) into a vein, under the supervision of a healthcare professional. A rapid infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath or itching. It may also be combined with other antibiotics to treat additional types of bacteria. Some people may develop local injection site reactions like pain, swelling, and redness. However, these are usually minor and temporary. Other side effects like wheezing, kidney (renal) injury, shortness of breath, flushing (sense of warmth in the face, ears, neck, and trunk) and decreased blood pressure may be seen occasionally. Inform your doctor if you have a history of an allergic reaction to this medication in the past. Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine. Some people may be advised blood tests to check the level of this medicine in their blood. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Uses of Covan

  • Severe bacterial infections

Side effects of Covan

Common
  • Breathlessness
  • Decreased blood pressure
  • Wheezing
  • Renal injury
  • Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Covan

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Covan works

Covan is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Quick Tips

  • You have been prescribed Covan to treat serious bacterial infections of the heart, blood, bones, and soft tissues.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • It should be taken slowly via a drip. Fast infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath or itching.
  • Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine.
  • Your doctor may get regular blood tests done to check the level of this medicine in your blood.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Brief Description

Indication

Septicaemia, Soft tissue infections, Osteomyelitis, Enterocolitis, Colitis, Serious staphylococcal or other Gm +ve infections, Bacterial endocarditis

Administration

IV Preparation Add 10 mL of SWI to 500-mg vial and 20 mL of SWI to 1-g vial to yield 50 mg/mL solution; further dilution is required, depending on method of administration Intermittent infusion: Dilute 500 mg with ?100 mL of diluent and 1 g with ?200 mL of diluent (NS or D5W) Continuous infusion: Dilute in sufficient amount to permit infusion over 24 hours IV Administration Intermittent (preferred): Administer over 60 minutes; not to exceed 10 mg/min Continuous: Administer over 24 hours

Adult Dose

Intravenous Severe staphylococcal or other Gram-positive infections, Endocarditis Adult: 500 mg 6 hrly, infused over at least 60 min or 1 g 12 hrly, infused over at least 100 min. Elderly: Dosage adjustment needed.

Child Dose

Intravenous Children Severe staphylococcal or other Gram-positive infections, Endocarditis <1 month: 15 mg/kg followed by 10 mg/kg IV q12hr for neonates in first week of life and q8hr thereafter up to 1 month of age; longer dosing intervals recommended in premature infants >1 month: 10 mg/kg/day IV divided q6hr; individual dose not to exceed 1 g

Renal Dose

Renal impairment: Patient on intermittent haemodialysis: Loading dose: 15-25 mg/kg on day 1, followed by 5-10 mg/kg maintenance dose after each dialysis run. Anuric patient (w/o kidney function) on dialysis: Initially, 15 mg/kg. Maintenance: 1.9 mg/kg 24 hrly. CrCl (ml/min) Dosage Recommendation <20 Longer intervals; determine by serum concentration monitoring. 20-49 Initially, 15-20 mg/kg/dose (usual: 750-1,500 mg) 24 hrly. >50 Initially, 15-20 mg/kg/dose (usual: 750-1,500 mg) 8-12 hrly.

Contraindication

Hypersensitivity to the drug; history of impaired hearing; IM administration.

Mode of Action

Vancomycin binds tightly to D-alanyl-D-alanine portion cell wall precursor causing blockage of glycopeptide polymerisation which produces immediate inhibition of cell wall synthesis and secondary damage to the cytoplasmic membrane.

Precaution

Patient w/ allergic reaction to teicoplanin, previous hearing loss, inflammatory bowel disease. Renal impairment. Elderly. Pregnancy and lactation. Monitoring Parameters Determine regularly serial tests of auditory function and serum or blood vancomycin concentrations during treatment. Periodic urinalysis and renal function tests. Monitor leukocyte count in prolonged therapy. Lactation: Drug enters breast milk; not recommended

Side Effect

>10% Erythematous rash on face and upper body (red neck or red man syndrome; related to infusion rate),Hypotension accompanied by flushing 1-10% Chills,Drug fever,Eosinophilia,Rash,Reversible neutropenia,Phlebitis <1% Nephrotoxicity,Ototoxicity (especially with large doses),Stevens-Johnson syndrome,Thrombocytopenia,Vasculitis Potentially Fatal: Stevens-Johnson syndrome; toxic epidermal necrolysis, blood dyscrasias such as neutropenia or thrombocytopenia.

Interaction

General anaesth may enhance the adverse effects of vancomycin. Increased risk of ototoxicity and nephrotoxicity w/ aminoglycosides, polymyxins, ciclosporin, cisplatin and loop diuretics. Increased potential of neuromuscular blockade w/ suxamethonium or vecuronium.

Buy Covan from Arogga

In Bangladesh, you can get the original Covan. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Covan in Bangladesh?

The latest price of Covan in Bangladesh is 225৳. You can buy Covan at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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SAFE
Consuming alcohol with Covan does not cause any harmful side effects.
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CONSULT YOUR DOCTOR
Covan may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Covan is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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SAFE
Covan does not usually affect your ability to drive.
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CAUTION
Covan should be used with caution in patients with kidney disease. Dose adjustment of Covan may be needed. Please consult your doctor. Regular monitoring of kidney function test and some blood tests is advised while you are taking this medicine.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Covan in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.