It is not known whether it is safe to consume alcohol with Vinorelbine. Please consult your doctor.
CONSULT YOUR DOCTOR
Vinorelbine is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Vinorelbine is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Vinorelbine does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Vinorelbine is safe to use in patients with kidney disease. No dose adjustment of Vinorelbine is recommended.
However, talk to your doctor if you have any underlying kidney disease.
CAUTION
Vinorelbine should be used with caution in patients with liver disease. Dose adjustment of Vinorelbine may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised while these patients are taking this medicine.
Medicine Overview of Vinorelbine 30mg Tablet
Introduction
Vinorelbine is an anti-cancer medication used in the treatment of breast cancer and non-small cell lung cancer.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to ... Show more
Uses of Vinorelbine
Breast cancer
Non-small cell lung cancer
Side effects of Vinorelbine
Common
Nausea
Vomiting
Weakness
Fatigue
Hair loss
Low blood platelets
Increased liver enzymes
Fever
Anemia (low number of red blood cells)
Bleeding
Constipation
How to use Vinorelbine
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vinorelbine works
Vinorelbine blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Quick Tips
Inform your doctor if you have a history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosu ... Show more
Do not take live or attenuated vaccines during therapy and avoid contact with people who receive them.
Use two methods of contraception while on this therapy and 3 months after it to avoid pregnancy.
Men should not father a child while on this therapy and 3 months post it. They should also seek guidance and counselling on sperm conservati ... Show more
Avoid contact with skin, eyes or mucosa as vinorelbine may cause irritation. Thoroughly wash the skin area, in case of skin contact with the ... Show more
Take vinorelbine preferably with a light meal to reduce nausea. Soft capsule gels of vinorelbine should not be taken with hot fluids, as the ... Show more
Vinorelbine is not recommended in children below 18 years.
Brief Description
Indication
Breast cancer, Ovarian cancer, Cervical cancer, Non-small cell lung cancer
Administration
IV Preparation
May be diluted in syringe or bag
Syringe: dilute to 1.5-3 mg/mL in NS or D5W
IV Bag: dilute to 0.5-2 mg/mL in NS, 1/2NS, D5W, D5/½NS ... Show more
Adult Dose
Oral
Non-small cell lung cancer
Adult: 60 mg/m2once wkly for 3 wk, may increase subsequently to 80 mg/m2 once wkly. If neutrophil count is < 500 cel ... Show more
Contraindication
Hypersensitivity to vinorelbine or other vinca alkaloids; severe current or recent infection (within last 2 wk); neutropenia; thrombocytopenia; severe ... Show more
Mode of Action
Vinorelbine, a semisynthetic vinblastine derivative, binds to tubulin and inhibits microtubule formation. This disrupts the formation of the mitotic s ... Show more
Precaution
Hepatic impairment. Compromised bone marrow reserve due to prior irradiation or chemotherapy; recovering marrow function from the effects of previous ... Show more
Side Effect
>10%
Leukopenia (92%),Granulocytopenia (90%),Anemia (83%),Elev AST (67%),Nausea (44%),Asthenia (36%),Constipation (35%),Fatigue (27%),Peripheral neur ... Show more
Interaction
Increased risk of granulocytopenia with cisplatin. Increased risk of neurotoxicity with paclitaxel, itraconazole, ketoconazole. Increased radiosensiti ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.