Coveram 4/5 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Coveram 4/5 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Coveram 4/5 may cause side effects which could affect your ability to drive.
Coveram 4/5 usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.
CAUTION
Coveram 4/5 should be used with caution in patients with kidney disease. Dose adjustment of Coveram 4/5 may be needed. Please consult your doctor.
Caution should be advised in patients with renal impairment.
CAUTION
Coveram 4/5 should be used with caution in patients with liver disease. Dose adjustment of Coveram 4/5 may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.
Medicine Overview of Coveram 4/5 4mg+5mg tablet
Introduction
Coveram 4/5 is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of futu...
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Uses of Coveram 4/5
Hypertension (high blood pressure)
Side effects of Coveram 4/5
Common
Ankle swelling
Headache
Tiredness
Palpitations
Increased potassium level in blood
Sleepiness
Cough
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Decreased blood pressure
Upset stomach
How to use Coveram 4/5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coveram 4/5 is to be taken empty stomach.
How Coveram 4/5 works
Coveram 4/5 is a combination of two medicines: Amlodipine and perindopril which lower blood pressure effectively. It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.
Quick Tips
You have been prescribed Coveram 4/5 for the treatment of high blood pressure.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Do not take Coveram 4/5 if you are pregnant or planning for pregnancy.
Brief Description
Indication
Indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled on monotherapy or as initial therapy in pati...
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Administration
Should be taken on an empty stomach.
Adult Dose
Hypertension
Indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled on monotherapy or as initial t...
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Renal Dose
Renal Impairment
CrCl <30 mL/min: Not recommended
CrCl 30-80 mL/min (mild or moderate renal impairment): Do not exceed 7/5 mg
Contraindication
History of idiopathic angioedema. Severe hypotension, shock (e.g. cardiogenic shock), left ventricular outflow tract obstruction (e.g. high grade aort...
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Mode of Action
Perindopril, a prodrug of perindoprilat, is an ACE inhibitor which prevents convertion of angiotensin I to angiotensin II, thereby increasing plasma r...
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Precaution
Patient w/ salt or volume depletion, severe obstructive coronary artery disease, renal artery and mitral and severe aortic stenosis, ischemic heart di...
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Side Effect
1-10%
Peripheral edema (7.2%)
Cough (3.2%)
Headache (2.5%)
Dizziness (2.5%)
Frequency Not Defined
Dermatologic: Rash
Digestive: Nausea, diarr...
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Interaction
Increased hypotensive effects w/ antihypertensive agents (e.g. β-blockers), diuretics, and vasodilators. May increase serum levels and toxicity of lit...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.