Out of stock

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Dacarzin

Name: Dacarzin 200mg/vial Injection
Brand: Beacon Pharmaceuticals PLC
SKU: 4925
Price: 909 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Injection - (200mg/vial)

Beacon Pharmaceuticals PLC

Generic: Dacarbazine

Safety Advices

বাংলা

English

CAUTION

Caution is advised when consuming alcohol with Dacarzin. Please consult your doctor.

CONSULT YOUR DOCTOR

Dacarzin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

CONSULT YOUR DOCTOR

Dacarzin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

UNSAFE

Dacarzin may cause side effects which could affect your ability to drive. Dacarzin may influence the ability to drive because of its central nervous system side effects.

CAUTION

Dacarzin should be used with caution in patients with kidney disease. Dose adjustment of Dacarzin may be needed. Please consult your doctor.

CAUTION

Dacarzin should be used with caution in patients with liver disease. Dose adjustment of Dacarzin may be needed. Please consult your doctor.

Medicine Overview of Dacarzin 200mg/vial Injection

Introduction

Dacarzin is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor. Dacarzin is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking...

... Show more

Uses of Dacarzin

Malignant melanoma
Hodgkin’s disease

Side effects of Dacarzin

Common

Nausea
Vomiting
Injection site pain
Decreased white blood cell count
Loss of appetite

How to use Dacarzin

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dacarzin works

Dacarzin is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

What if you forget to take Dacarzin?

If you miss a dose of Dacarzin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

Dacarzin is given as an injection into veins under the supervision of a doctor.

Brief Description

Indication

Metastatic melanoma, Hodgkin's disease, Soft tissue sarcoma

Administration

IV Preparation Reconstitute with a 9.9 mL (100 mg vial) or 19.7 mL (200 mg vial) of SWI to obtain a 10 mg/mL soln For infusion, dilute with D5W or NS up to 250 mL IV Administration IVP over 1 min (may be irritant & painful) OR infusion over 15-60 min

Adult Dose

Intravenous Metastatic melanoma Adult: 2-4.5 mg/kg daily for 10 days, repeat at 4-wk intervals or 200-250 mg/m2 BSA daily for 5 days, repeat at 3-wk intervals or 850 mg/m2 BSA by infusion, repeat at 3-wk intervals. Hodgkin's disease Adult: 150 mg/m2 BSA daily for 5 days, repeat every 4 wk or 375 mg/m2 BSA every 15 days in combination with other agents. Soft tissue sarcoma Adult: 250 mg/m2 BSA daily for 5 days repeated every 3 wk. Usually given with doxorubicin.

Child Dose

Hodgkin's Disease With other antineoplastics, eg ABVD Dosage dependent on protocol150 mg/m² IV qDay for 5 days, repeat q4Weeks OR 375 mg/m² IV on Day 1; repeat every 15 Days

Contraindication

Bone marrow suppression; hypersensitivity.

Mode of Action

The exact mechanism of action is still unclear but it appears to form methylcarbonium ions that attack nucleophilic groups by attaching to the 7-position of guanine on DNA. It also cross-links DNA strands leading to inhibition of DNA, RNA and protein synthesis.

Precaution

Hepatic or renal impairment. Pregnancy, lactation. Lactation: not known if excreted in breast milk, do not nurse

Side Effect

>10% Nausea (>90%),Vomiting(>90%),Injection site pain,Leukopenia,Thrombocytopenia 1-10% Alopecia,Rash,Photosensitivity,Anorexia,Metallic taste,Flu-like syndrome Frequency Not Defined Anaphylaxis,Photosensitivity (rare),Cerebral hemorrhage,Seizure,Myelosuppression,Hepatic necrosis,Hepatic vein thrombosis,Hepatotoxicity Potentially Fatal: Myelosuppression; hepatotoxicity, anaphylaxis.

Pregnancy Category Note

Pregnancy Category: C Lactation: not known if excreted in breast milk, do not nurse

Interaction

Impairs immune response to vaccines; possible infection after admin of live vaccines. Effect increased by CYP1A2 inhibitors e.g. amiodarone, ciprofloxacin, fluvoxamine, ketoconazole, lomefloxacin, ofloxacin and rofecoxib. Effect decreased by CYP1A2 inducers e.g. aminoglutethimide, carbamazepine, phenobarbital and rifampicin.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Dacarzin

Injection - (200mg/vial)

Beacon Pharmaceuticals PLC

Generic: Dacarbazine

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

Cashback

৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.