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Ajardy M 500

Tablet-(5mg+ 500mg)
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Ziska Pharmaceuticals Ltd.

Generic: Empagliflozin + Metformin Hydrochloride

8 Tablets (1 Strip)
৳ 109.62
৳ 120
9% OFF

Medicine Overview of Ajardy M 500 5mg+ 500mg Tablet

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Introduction

Ajardy M 500 is a combination of empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor and metformin hydrochloride, a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both empagliflozin and metformin hydrochloride is appropriate.Ajardy M 500 is indicated to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease. However, the effectiveness of Ajardy M 500 on reducing the risk of cardiovascular death in adults with type 2 diabetes mellitus and cardiovascular disease has not been established.

Uses of Ajardy M 500

Ajardy M 500 use as a treatment of adults with type 2 diabetes mellitus.

Side effects of Ajardy M 500

  • Nausea
  • Vomiting
  • Diarrhea
  • Headaches
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Increased urination
  • Weight loss

How to use Ajardy M 500

Take Ajardy M 500 in the dose and duration prescribed by your doctor. Swallow it whole. Don't chew, crush, or break it. Ajardy M 500 should be taken with food.

How Ajardy M 500 works

By blocking SGLT2,Ajardy M 500 prevents glucose from being reabsorbed and allows it to be excreted in the urine.Also work by decreasing the production of glucose in the liver and increasing the sensitivity of cells to insulin and lowers blood sugar levels.

What if you forget to take Ajardy M 500 ?

If you forget to take yourAjardy M 500 , take them as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at the usual time. Avoid taking two doses at the same time.

Brief Description

Indication

Indicated for the treatment of adults with Type 2 Dabetes Mellitus as an adjunct to diet and exercise.

Administration

The dosage should be adjusted according to effectiveness and tolerability. Take this combination twice a day, with meals. To reduce the gastrointestinal side effects associated with Metformin Hydrochloride, dose escalation should be gradual. The maximum recommended daily dose of Metformin Hydrochloride is 2000 mg, while Empagliflozin is 25 mg.

Adult Dose

The standard starting dose for empagliflozin + metformin hydrochloride is 5 mg of empagliflozin and 500 mg of metformin hydrochloride once daily. The dose can be gradually increased to a maximum of 25 mg of empagliflozin and 2,000 mg of metformin hydrochloride per day.

Child Dose

The safety and efficacy of this medication in children under the age of 18 has not been established.

Renal Dose

Before starting this combination with a renally impaired patient, assess their renal function.In patients with an eGFR below 45 mL/min/1.73 m2 is contraindicated.

Contraindication

•Type 1 diabetes •Diabetic ketoacidosis (DKA) •Severe kidney disease (eGFR < 30 mL/min/1.73 m2) •Severe liver disease •Heart failure •Active bladder infection •Recent surgery or major trauma •Hypersensitivity to empagliflozin or metformin hydrochloride History of lactic acidosis. • History of urinary tract infections or genital yeast infections •Risk of dehydration •Elderly patients

Mode of Action

By blocking SGLT2, empagliflozin prevents glucose from being reabsorbed and allows it to be excreted in the urine and decreasing the production of glucose in the liver and increasing the sensitivity of cells to insulin .It work synergistically to lower blood sugar levels more effectively.

Precautions

Empagliflozin + metformin hydrochloride should not be used by individuals with - • Type 1 diabetes. • Diabetic ketoacidosis • Severe kidney disease • Severe liver diseases • Heart failure. • Active bladder infection. • Recent surgery or significant trauma

Side Effect

Serious side effects: • Diabetic ketoacidosis (DKA) • Lactic acidosis • Hypoglycemia (low blood sugar) • Dehydration • Urinary tract infections • Female genital mycotic infections • urticaria, dysuria • Vaginal moniliasisia Common side effects : • Increased urination • Thirst • Dry mouth • Nausea • Vomiting • Diarrhea • Abdominal pain • Headache • Dizziness • Fatigue • Weight loss

Pregnancy & Lactation Category Note

Pregnancy: It is s not recommended for use during pregnancy due to potential risk to a fetus especially during the second and third trimesters. Lactation: Empagliflozin is excreted in breast milk and may be harmful to the nursing infant. Metformin hydrochloride is also excreted in breast milk, but it is unclear whether it can harm a nursing infant.

Interaction

It may interact with other medications, including: •Insulin: Empagliflozin + metformin hydrochloride can increase the risk of hypoglycemia (low blood sugar) when used with insulin. •Sulfonylureas: Empagliflozin + metformin hydrochloride can also increase the risk of hypoglycemia when used with sulfonylureas, another type of medication used to treat type 2 diabetes. •Meglitinides: Empagliflozin + metformin hydrochloride can also increase the risk of hypoglycemia when used with meglitinides, another type of medication used to treat type 2 diabetes. •Thiazolidinediones: Empagliflozin + metformin hydrochloride may increase the risk of heart failure when used with thiazolidinediones, another type of medication used to treat type 2 diabetes. •Alpha-glucosidase inhibitors: Empagliflozin + metformin hydrochloride may decrease the effectiveness of alpha-glucosidase inhibitors, another type of medication used to treat type 2 diabetes. •Beta-blockers: Empagliflozin + metformin hydrochloride may mask the symptoms of hypoglycemia, such as increased heart rate and sweating, when used with beta-blockers. •ACE inhibitors: Empagliflozin + metformin hydrochloride may increase the risk of hypotension (low blood pressure) when used with ACE inhibitors. •ARBs: Empagliflozin + metformin hydrochloride may increase the risk of hypotension when used with ARBs. •Diuretics: Empagliflozin + metformin hydrochloride may increase the risk of dehydration when used with diuretics. •Steroids: Empagliflozin + metformin hydrochloride may increase the risk of hyperglycemia (high blood sugar) when used with steroids. •Thyroid hormones: Empagliflozin + metformin hydrochloride may increase the risk of hypoglycemia when used with thyroid hormones.

Storage Conditions

Store below 30°C temperature, protected from light & moisture. Keep out of the reach of children.

Buy Ajardy M 500 from Arogga

In Bangladesh, you can get the original Ajardy M 500. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Ajardy M 500 in Bangladesh?

The latest price of Ajardy M 500 in Bangladesh is 109.62৳. You can buy Ajardy M 500 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume Ajardy M 500 with alcohol.
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UNSAFE
Ajardy M 500 should not be used during pregnancy.
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UNSAFE
Ajardy M 500 should not be used during breastfeeding.
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CAUTION
Ajardy M 500 may cause dizziness or orthostatic hypotension (low blood pressure when standing up), which can impair ability to drive.
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CONSULT YOUR DOCTOR
It is important to talk to your doctor about the risks and benefits of taking Ajardy M 500 before starting treatment. Ajardy M 500 should not be given to patients with serious kidney disease.
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CAUTION
Ajardy M 500 may not be suitable for patients with severe liver impairment.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.