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Safety Advices
বাংলা
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CAUTION
Caution is advised when consuming alcohol with Dapsone. Please consult your doctor.
CONSULT YOUR DOCTOR
Dapsone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Dapsone is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE
Dapsone does not usually affect your ability to drive.
CONSULT YOUR DOCTOR
There is limited information available on the use of Dapsone in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Dapsone in patients with liver disease. Please consult your doctor.
Medicine Overview of Dapsone 50mg Tablet
Introduction
Dapsone belongs to a class of drugs known as anti-leprotic medicines. It is used to treat leprosy and acne. It works by stopping the growth of disease causing organisms in the body. It also helps to reduce redness and swelling associated with acne (commonly known as pimples). Dapsone should be used in the dose and duration as advised by your doctor. It should be taken with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for...
... Show moreUses of Dapsone
- Leprosy
Side effects of Dapsone
Common
- Rash
- Fever
How to use Dapsone
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dapsone may be taken with or without food, but it is better to take it at a fixed time.
How Dapsone works
Dapsone is an anti-leprotic medication. It works by stopping the production of folic acid in certain bacteria, thereby stopping them from growing.
Quick Tips
- When used long term, your doctor may monitor amount of blood cells in your blood regularly.
- Inform your doctor if your condition does not improve or you get eye or nerve problems.
Brief Description
Indication
Pneumonia, Acne, Leprosy, Dermatitis herpetiformis
Adult Dose
Dermatitis Herpetiformis
50 mg PO qDay, titrate to 300 mg qDay or higher to achieve desired effect
Reduce dose to minimum effective dose within the range of 50-300 mg qDay as soon as possible
Leprosy
100 mg PO qDay, in combination with other antileprosy drugs
Tuberculoid or Lepromatous Disease
100 mg PO qDay with rifampin 600 mg PO qDay
Child Dose
Child: PO 2 mg/kg, max 100 mg q24h
4 mg/kg, max 200 mg Once weekly
Contraindication
Hypersensitivity. Severe anaemia, porphyria.
Mode of Action
Dapsone inhibits folic acid synthesis by preventing normal bacterial utilization of PABA (PABA).
Precaution
G6PD deficiency, methaemoglobin or Hb M. Perform regular blood counts and monitor liver function regularly. Pregnancy and lactation.
Lactation: Enters breast milk; not recommended (AAP Committee states "compatible with nursing")
Side Effect
1-10%
Hemolysis,Methemoglobinemia
<1%
Reactional states (ie, abrupt changes in clinical activity occurring during any leprosy treatment; classified as reversal of erythema nodosum leprosum reactions),Insomnia,Headache,Exfoliative dermatitis,Photosensitivity,Nausea,Vomiting,Anemia,Leukopenia,Agranulocytosis,Hepatitis,Cholestatic jaundice,Peripheral neuropathy (usually in nonleprosy patients),Blurred vision,Tinnitus,SLE
Potentially Fatal: Agranulocytosis, serious cutaneous hypersensitivity reactions, exfoliative dermatitis.
Pregnancy Category Note
Pregnancy category: C
Lactation: Enters breast milk; not recommended (AAP Committee states "compatible with nursing")
Interaction
Decreased serum conc of dapsone when used with rifampicin. Increased plasma conc with probenecid, trimethoprim. Antagonize clofazimine.