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Safety Advices
বাংলা
English
UNSAFE
Derat may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Derat may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Derat is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Because of its low milk levels and lack of sleepiness, use of Derat would not be expected to cause any adverse effects in breastfed babies.
SAFE
Derat does not usually affect your ability to drive.
CAUTION
Derat should be used with caution in patients with kidney disease. Dose adjustment of Derat may be needed. Please consult your doctor.
CAUTION
Derat should be used with caution in patients with liver disease. Dose adjustment of Derat may be needed. Please consult your doctor.
Medicine Overview of Derat 5mg Tablet
Introduction
Derat belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions. It relieves symptoms like itching, swelling and rashes. Derat may be taken with or without food. The dose may vary depending on what you are taking it for. Take it as it has been prescribed by your doctor. You may need this medicine only on days you have symptoms, or you may need to take it every day to prevent symptoms from happening. If you stop taking it earlier than advised, your symptoms may come back. This medicine is generally very...
... Show moreUses of Derat
- Allergic conditions
Side effects of Derat
Common
- Sleepiness
How to use Derat
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Derat may be taken with or without food, but it is better to take it at a fixed time.
How Derat works
Derat is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.
What if you forget to take Derat?
If you miss a dose of Derat, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Derat to help relieve allergy symptoms such as itching, swelling, and rashes.
- As compared to other similar medications, it is much less likely to make you feel sleepy.
- Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
- Do not drink alcohol while taking this medication as it may cause increased sleepiness.
- Stop taking Derat at least three days before taking an allergy test as it can affect the test results.
Brief Description
Indication
Itching, Sneezing, Watery eyes, Allergic conditions, Runny nose, Hives, Skin rash, Common cold
Administration
May be taken with or without food.
Adult Dose
Oral
Allergic conditions
Adult: 5 mg once daily.
Hepatic Impairment: Initially, 5 mg every other day.
Child Dose
Oral
Allergic conditions
Child: 12 years or over : 5 mg once daily.
Child 6-11 years : 2.5 mg once daily.
Child 12 months-5 years : 1.25 mg (2.5 ml syrup) once daily.
Child 6 months-11 months : 1 mg (2 ml syrup) once daily.
Renal Dose
Initially, 5 mg every other day.
Contraindication
Hypersensitivity.
Mode of Action
Desloratadine is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils.
Precaution
Severe renal or hepatic failure; children <6 mth, elderly, epilepsy, pregnancy and lactation.
Lactation: excretion in milk unknown/not recommended
Side Effect
>10%
Headache (14%),Fever (12%),Irritability (12%),Diarrhea (15%),Upper respiratory infection (11%),Cough (11%)
1-10%
Dizziness (4%),Somnolence (2%),Dizziness (4%),Fatigue (2%),Erythema (2%),Macupopular rash (3%),Dysmenorrhea (2%),Urinary tract infection (4%),Bronchitis (6%),Epistaxis (3%)
Pregnancy Category Note
Pregnancy The limited available data in pregnant women are not sufficient to inform a drug-associated risk for major birth defects and miscarriage; there are no adequate and well-controlled studies in pregnant women Reproductive potential There are no data available on human infertility associated with desloratadine Female: There were no clinically relevant effects of desloratadine on female fertility in rats Male: A male specific decrease in fertility occurred at an oral desloratadine dose of ?12 mg/kg in rats (approximately 65 times the RHD); male fertility was unaffected at a desloratadine dose of 3 mg/kg (approximately 10 times the RHD) Lactation Desloratadine...
... Show moreInteraction
Potential increase in plasma concentrations w/ drugs affecting hepatic microsomal enzymes (e.g. azithromycin, cimetidine, erythromycin, fluoxetine, ketoconazole).
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