Detomax may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Detomax may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Detomax is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
NOT RELEVANT
Not relevant, as Detomax is intended for use in hospitalised patients.
SAFE IF PRESCRIBED
Detomax is safe to use in patients with kidney disease. No dose adjustment of Detomax is recommended.
CAUTION
Detomax should be used with caution in patients with liver disease. Dose adjustment of Detomax may be needed. Please consult your doctor.
Medicine Overview of Detomax 200mcg/2ml Injection
Introduction
Detomax is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It may also be used for awake sedation during diagnostic and surgical procedures.
Detomax is given as ...
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Uses of Detomax
Sedative
Side effects of Detomax
Common
Decreased blood pressure
Dryness in mouth
How to use Detomax
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Detomax works
Detomax works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.
Quick Tips
Detomax is given as an infusion into the veins by healthcare professionals only.
Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
IV Preparation
Dilute in NS
IV Administration
Infuse loading dose over 10 min
Adult Dose
ICU Sedation
Load: 1 mcg/kg IV over 10 minutes
Maintenance 0.2-1.4 mcg/kg/hr IV
Titrate less frequently than q30min to prevent hypotension
Fibe...
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Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment
Dose reduction may be required
Contraindication
2nd or 3rd degree AV block (unless paced), uncontrolled hypotension, acute cerebrovascular disorders.
Mode of Action
Centrally acting alpha2-adrenoceptor agonist that has sedative and anesthetic properties possibly by activating G-proteins in the brainstem, which res...
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Precaution
Significant CV dysfunction, advanced heart block &/or severe ventricular dysfunction, hypovolemia, DM, chronic HTN. Renal & hepatic impairment. Do not...
Pregnancy
There are no adequate and well-controlled studies of use in pregnant women
In an in vitro human placenta study, placental transfer of de...
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Interaction
Enhanced pharmacologic effects of anaesth, sedatives, hypnotics, opiate agonists, other vasodilators or drugs that have negative chronotropic effects ...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.