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Calumide 50
Healthcare Pharmaceuticals Ltd.
Generic: Bicalutamide
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Calumide 50. Please consult your doctor.
UNSAFE
Calumide 50 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
CONSULT YOUR DOCTOR
Information regarding the use of Calumide 50 during breastfeeding is not available. Please consult your doctor.
SAFE
Calumide 50 does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Calumide 50 is safe to use in patients with kidney disease. No dose adjustment of Calumide 50 is recommended.
CAUTION
Calumide 50 should be used with caution in patients with liver disease. Dose adjustment of Calumide 50 may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable while you are taking this medicine.
Medicine Overview of Calumide 50mg Tablet
Introduction
Calumide 50 is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone. Calumide 50 should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it...
... Show moreUses of Calumide 50
- Prostate cancer
Side effects of Calumide 50
Common
- Anemia (low number of red blood cells)
- Rash
- Abdominal pain
- Breast enlargement in male
- Breast tenderness
- Constipation
- Decreased appetite
- Decreased libido
- Depression
- Dizziness
- Indigestion
- Flatulence
- Hot flashes
- Increased liver enzymes
- Nausea
- Sleepiness
- Weakness
- Weight gain
How to use Calumide 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calumide 50 may be taken with or without food, but it is better to take it at a fixed time.
How Calumide 50 works
Calumide 50 blocks the effect of the natural male hormones on the growth of prostate cells. Calumide 50 also blocks the undesired effects of androgens in females such as excessive hair growth and acne.
Quick Tips
- You have been prescribed Calumide 50 for the treatment of prostate cancer.
- Take it with or without food, preferably at the same time every day.
- It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
- If you are diabetic, monitor your blood glucose regularly while taking Calumide 50.
- Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Do not stop taking the medication without talking to your doctor first.
Brief Description
Indication
Prostate Cancer
Administration
May be taken with or without food.
Adult Dose
Oral
Palliative treatment of advanced prostate cancer
Adult: When used with gonadorelin analogue: Usual dose: 50 mg once daily. May be started with or at least 3 days before starting gonadorelin analogue therapy.
Monotherapy or adjuvant therapy to surgery or radiotherapy in locally advanced prostatic cancer
Adult: 150 mg once daily.
Contraindication
Hypersensitivity. Females, children. Pregnancy, lactation.
Mode of Action
Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin, thus preventing the growth of normal and malignant prostatic tissue.
Precaution
Monitor liver function regularly in hepatically impaired patients on prolonged therapy. Monitoring serum levels of Prostate Specific Antigen (PSA) may be useful in evaluating the patient's clincial progress.
Lactation: Bicalutamide is not indicated for use in women.
Side Effect
>10%
Hot flashes (53%),General pain (35%),Back pain (25%),Asthenia (22%),Constipation (22%),Pelvic pain (21%),Infection (18%),Nausea (15%),Dyspnea (13%),Edema (13%),Peripheral edema (13%),Diarrhea (12%),Hematuria (12%),Nocturia (12%),Abdominal pain (11%),Anemia (11%)
1-10%
Gynecomastia (9%),Rash (9%),UTI (9%),Chest pain (8%),Hypertension (8%),Vomiting (8%),Flu like symptoms (7%),Headache (7%),LFTs elevation (7%),Weight loss (7%),Anorexia (6%),Breast pain (6%),Anxiety (5%)
Arthritis (5%)
Pregnancy Category Note
Pregnancy Contraindicated for use in pregnant women because it can cause fetal harm; not indicated for use in females; there are no human data on use in pregnant women; in animal reproduction studies, oral administration of bicalutamide to pregnant rats during organogenesis caused abnormal development of reproductive organs in male fetuses at exposures approximately 0.7 to 2 times the human exposure at recommended dose Lactation Not indicated for use in pregnant women; there is no information available on presence of bicalutamide in human milk, or on effects on breastfed infant or on milk production; bicalutamide has been detected in rat...
... Show moreInteraction
Enhances effect of coumarin anticoagulants.
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