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Biva

Name: Biva 250mg/5ml Injection
Brand: Healthcare Pharmaceuticals Ltd.
SKU: 54872
Price: 9090 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Injection - (250mg/5ml)

Healthcare Pharmaceuticals Ltd.

Generic: Bivalirudin

Safety Advices

বাংলা

English

UNSAFE

It is unsafe to consume alcohol with Biva.

SAFE IF PRESCRIBED

Biva is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

CONSULT YOUR DOCTOR

Biva is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

NOT RELEVANT

Not relevant, as Biva is intended for use in hospitalised patients.

CAUTION

Biva should be used with caution in patients with kidney disease. Dose adjustment of Biva may be needed. Please consult your doctor. Use of Biva is not recommended in patients with severe kidney disease and patients undergoing dialysis.

SAFE IF PRESCRIBED

Biva is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Biva may not be needed in these patients. Please consult your doctor.

Medicine Overview of Biva 250mg/5ml Injection

Introduction

Biva belongs to a group of medicines known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart. Biva is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It is given as an infusion (drip) into a vein under the supervision of a doctor. You...

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Uses of Biva

Heart attack
Unstable angina

Side effects of Biva

Common

Bruise

How to use Biva

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Biva works

Biva is an anticoagulant that prevents the formation of harmful blood clots.

Quick Tips

It is a hospital only medicine. It is given by your nurse or doctor as an infusion (drip) into a vein.

Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).

Inform your doctor if you are taking other blood thinners or medicines to prevent blood clots.

Brief Description

Indication

As an anticoagulant in percutaneous coronary intervention

Administration

IV Preparation To each 250 mg vial add 5 mL SWI Gently swirl until all material is dissolved Dilute each vial in 50 mL of D5W or NS to yield a final concentration of 5 mg/mL If low-rate infusion is used after initial infusion, a lower concentration bag should be prepared Inspect for particulate matter and discoloration prior to administration Do not use preparations containing particulate matter Reconstituted drug will be a clear to slightly opalescent, colorless to slightly yellow solution IV Administration Initial bolus injection followed by continuous infusion

Adult Dose

Intravenous As an anticoagulant in percutaneous coronary intervention Adult: Initially, 0.75 mg/kg inj followed by an infusion of 1.75 mg/kg/hr during procedure and up to 4 hours postprocedure. If needed, may continue infusion at 0.25 mg/kg/hr for 4-12 hours. Hepatic impairment: No dosage adjustment needed.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation 30-59 Reduced infusion to 1.4 mg/kg/hr. <30 Contraindicated. Dialysis Contraindicated.

Contraindication

Active major bleeding. CrCl <30 mL/min and dialysis-dependent patients. Severe uncontrolled HTN; subacute bacterial endocarditis.

Mode of Action

Bivalirudin is a synthetic 20-amino acid analogue of the naturally occurring hirudin. It is a specific and reversible direct thrombin inhibitor thats works by binding to the catalytic and anionic exosite of circulating and clot-bound thrombin. It is used as an anticoagulant in percutaneous coronary intervention.

Precaution

Increased risk of potentially fatal thrombosis during brachytherapy procedure. Patients at high risk of serious bleeding; recent major surgery or puncture of large vessels or organ biopsy. Renal impairment. Pregnancy, lactation, elderly.

Side Effect

>10% Back pain (42%) General pain (15%) Nausea (15%) Hemorrhage, minor (13.6%) Headache (12%) Hypotension (12%) 1-10% Injection site pain (8%) Insomnia (7%) Pelvic pain (6%) Hypertension (6%) Anxiety (6%) Vomiting (6%) Bradycardia (5%) Dyspepsia (5%) Abdominal pain (5%) Fever (5%) Nervousness (5%) Urinary retention (4%) Hemorrhage, major (2.3%) >3g/dL fall in Hgb (1.9%) TIMI minor bleeding (1.3%) RBC transfusions (1.3%)

Pregnancy Category Note

Pregnancy There are no data available in pregnant women to inform a drug-associated risk of adverse developmental outcomes Animal data Reproduction studies in rats and rabbits administered subcutaneously doses up to 1.6 times and 3.2 times maximum recommended human dose (MRHD) of 15 mg/kg/day based on body surface area (BSA) during organogenesis, respectively, revealed no evidence of fetal harm Lactation Not known whether drug is present in human milk; no data are available on effects on breastfed child or on milk production; developmental and health benefits of breastfeeding should be considered along with clinical need for therapy and any potential...

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Interaction

May increase risk of bleeding when used w/ thrombolytics, oral anticoagulants or drugs that affect platelet function.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Biva

Injection - (250mg/5ml)

Healthcare Pharmaceuticals Ltd.

Generic: Bivalirudin

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

Cashback

৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.