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Tobicin

Name: Tobicin 300mg Nebuliser Solution
Brand: Unimed Unihealth Pharmaceuticals Ltd.
SKU: 55108
Price: 136.35 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Nebuliser Solution - (300mg)

Unimed Unihealth Pharmaceuticals Ltd.

Generic: Tobramycin Sulphate

Medicine Overview of Tobicin 300mg Nebuliser Solution

বাংলা

English

Indication

Cystic fibrosis

Adult Dose

Inhalation Cystic fibrosis Indicated for management Pseudomonas aeruginosa in patients with cystic fibrosis Adult: One single-use ampoule (300 mg) 12 hrly, inhaled from a suitable nebuliser for 28 days, then stop for 28 days and repeat in cycles of 28 days as needed.

Child Dose

Inhalation Cystic fibrosis Indicated for management Pseudomonas aeruginosa in patients with cystic fibrosis Child: >6 yr : 300 mg 12 hrly, inhaled from a suitable nebuliser for 28 days, then stop for 28 days and repeat in cycles of 28 days as needed.

Renal Dose

Renal impairment: Dosage adjustment needed.

Contraindication

Hypersensitivity to aminoglycosides; pregnancy.

Mode of Action

Tobramycin acts by binding to 30S ribosomal subunits thus interfering with bacterial protein synthesis. It is active against many aerobic gram-negative bacteria and some aerobic gram-positive bacteria but inactive against Chlamydia, fungi, viruses, and most anaerobic bacteria.

Precaution

Preexisting renal and auditory or vestibular impairment; dehydration; neuromuscular blockade, muscular disorders (e.g. myasthenia gravis, parkinsonism); neonates; elderly; lactation. Lactation: Unknown whether inhaled tobramycin will reach sufficient concentration to be distributed in breast milk; because of the potential for ototoxicity and nephrotoxicity in infants, a decision should be made whether to terminate breastfeeding or discontinue inhaled tobramycin

Side Effect

>10% Voice alteration (12.8%) 1-10% Myalgia (4.7%),Laryngitis (4.3%),Tinnitus (3%),Epistaxis (3%)

Interaction

Increased nephrotoxicity or ototoxicity with etacrynic acid, furosemide, other aminoglycosides, cefalotin, cisplatin, vancomycin, piperacillin, ciclosporin, amphotericin B. Decrease serum tobramycin levels with miconazole. Potentially Fatal: Increased neuromuscular-blocking activity with magnesium and other neuromuscular-blocking agents.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Tobicin

Nebuliser Solution - (300mg)

Unimed Unihealth Pharmaceuticals Ltd.