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Doxorif 400
Sharif Pharmaceuticals Ltd.
Generic: Doxophylline
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Doxorif 400. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Doxorif 400 during pregnancy is not available. Please consult your doctor.
SAFE IF PRESCRIBED
Doxorif 400 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE
Doxorif 400 does not usually affect your ability to drive.
CONSULT YOUR DOCTOR
There is limited information available on the use of Doxorif 400 in patients with kidney disease. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Doxorif 400 in patients with liver disease. Please consult your doctor.
Medicine Overview of Doxorif 400mg Tablet
Introduction
Doxorif 400 is used to treat and prevent symptoms of asthma and chronic obstructive pulmonary disorder (a lung disorder in which flow of air to the lung is blocked). It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe. Doxorif 400 can be taken with the food in evening. But take it at the same time every day to get the most benefit. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms....
... Show moreUses of Doxorif 400
- Chronic obstructive pulmonary disease (COPD)
- Asthma
Side effects of Doxorif 400
Common
- Upset stomach
- Vomiting
- Headache
- Nausea
- Restlessness
How to use Doxorif 400
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doxorif 400 may be taken with or without food, but it is better to take it at a fixed time. Avoid Doxorif 400 with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
How Doxorif 400 works
Doxorif 400 is a bronchodilator. It works by relaxing the muscles of the airways and widens airways. This makes breathing easier.
Quick Tips
- You have been prescribed Doxorif 400 for prevention and treatment of asthma and chronic obstructive pulmonary disease (COPD).
- It should be taken at the same time each day, preferably in the evening after food.
- It does not work right away and should not be used to relieve sudden breathing problems. Always keep a fast-acting (rescue) inhaler with you.
- Your doctor may take regular blood test to monitor potassium level and the level of this medicine in your body.
- Notify your doctor if you have ever been diagnosed with kidney, liver or heart disease, or if you have a smoking history. Your dose may need to be adjusted.
- Do not discontinue use without consulting your doctor, even if you feel better.
Brief Description
Indication
COPD (Chronic Obstructive Pulmonary Disease), bronchial asthma
Adult Dose
Tablet Adults: Conventional Tablet 400mg 1 to 3 times a day. Sustained release tablet: 400 mg sustained release tablet once a day. Single dose, administration in the evening reduces nocturnal, symptoms and helps to keep the patients complaint free during the day. However, in certain cases, 400 mg tablet twice daily is recommended on the basis of the clinical response and according to disease severity. Doses as high as 1200mg/day (400 mg 3 times day) may also be prescribed. Elderly: The dosage may be decreased according to medical prescription in the very elderly patients with concomitant cardiovascular, hepatic, renal and...
... Show moreChild Dose
Tablet Children >12 years: 200 mg 2 or 3 times daily. Syrup Children> 12 years: 10 ml, 2 or 3 times daily. Children<12 years: 6 mg/kg/dose twice daily. In case of unsatisfactory response it can be increased up to 9 mg/kg/dose twice daily under medical supervision.
Contraindication
This is contraindicated for individuals who have shown hypersensitivity to Doxofylline and its components. It is also contraindicated in patients with acute myocardial infarction, hypotension, and in lactating women.
Mode of Action
Doxofylline is a theophylline derivative. Similarly, its mechanism of action is related to the inhibition of phosphodiesterase activities, resulting in bronchodilating effects.
Precaution
Use with caution in patients with hypoxemia, hyperthyroidism, liver disease, renal disease, in those with history of peptic ulcer and in elderly. Frequently, patients with Congestive Heart Failure (CHF) have markedly prolonged drug serum levels following discontinuation of Doxofylline.
Side Effect
Nausea, vomiting, epigastric pain, cephalalgia, irritability, insomnia, tachycardia, extrasystole, tachypnea and occasionally, hyperglycemia and albuminuria, may occur. If a potential oral overdose is established, the patient may present with severe arrhythmias and seizure; these symptoms could be the first sign of an intoxication. Adverse reactions may cause the withdrawal from treatment; a lower dose rechallenge may start only after the advice of a physician.
Interaction
Other xanthine derivatives, ephedrine, phenytoin & other anticonvulsants, erythromycin, troleandomycin, lincomycin, clindamycin, allopurinol, cimetidine, ranitidine, propranolol, flu vaccine.
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