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Duphaston 10
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Dydrogesterone
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Duphaston 10. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Duphaston 10 during pregnancy is not available. Please consult your doctor.
SAFE IF PRESCRIBED
Duphaston 10 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Duphaston 10 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Duphaston 10 in patients with kidney disease. Please consult your doctor.
CAUTION
Duphaston 10 should be used with caution in patients with liver disease. Dose adjustment of Duphaston 10 may be needed. Please consult your doctor.
Use of Duphaston 10 is not recommended in patients with severe liver disease.
Medicine Overview of Duphaston 10mg Tablet
Introduction
Duphaston 10 is used to treat female infertility, various menstrual problems including painful, or irregular periods, Premenstrual syndrome (PMS) and endometriosis. It helps to restart periods that have stopped before the menopause and to prevent unusually heavy period. Duphaston 10 should be taken as your doctor advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. The most...
... Show moreUses of Duphaston 10
- Female infertility
- Pain during menstruation
- Premenstural syndrome (PMS)
- Abnormal uterine bleeding
- Endometriosis
- Amenorrhea
Side effects of Duphaston 10
Common
- Headache
- Nausea
- Breast pain
How to use Duphaston 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duphaston 10 may be taken with or without food, but it is better to take it at a fixed time.
How Duphaston 10 works
Duphaston 10 is a progestin (female hormone). It works by regulating the healthy growth and normal shedding of the womb lining. This action helps re-establish a regular menstrual cycle in conditions where a lack of progesterone causes menstrual problems, such as in premenstrual syndrome, painful or absent menstrual periods, and endometriosis. It also helps in the treatment of infertility by stimulating the womb lining to prepare for a pregnancy.
Quick Tips
- Duphaston 10 is used for a wide range of menstrual disorders and to maintain a healthy womb lining for the ongoing pregnancy.
- It may also be used in women who have suffered repeated miscarriages.
- In case you have suffered repeated miscarriages, seek regular prenatal care. Avoid smoking, alcohol and limit your caffeine intake as these may lead to miscarriage.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
- Inform your doctor if you have a history of liver disease or depression.
Brief Description
Indication
Endometriosis, Miscarriage, Menstrual disorders, Infertility, Dysmenorrhea, Dysfunctional uterine bleeding, Premenstrual syndrome, Hormone replacement therapy
Administration
May be taken with or without food.
Adult Dose
Oral
Endometriosis
Adult: 10 mg bid-tid cyclically or continuously.
Recurrent miscarriage
Adult: 10 mg bid given cyclically until conception, then continuously until wk 20 of pregnancy, after which dose may be gradually reduced.
Menstrual disorders
Adult: 10 mg bid in a cyclical regimen.
Threatened miscarriage
Adult: Initially, 40 mg followed by 10 mg or more every 8 hr, continued for a wk after symptoms are relieved. Reduce dose gradually after that unless symptoms return.
Infertility
Adult: 10 mg bid.
Endometrial protection during menopausal hormonal replacement therapy
Adult: 10 mg 1-2 times daily in a cyclical regimen or 5 mg daily.
Contraindication
Hypersensitivity; pregnancy. Undiagnosed abnormal vag bleeding, thromboembolic disorders, history or existing cerebrovascular or coronary artery disease, missed or incomplete abortion, known or suspected carcinoma of the breast or genital organs, severe hepatic dysfunction, as a diagnostic test for pregnancy.
Mode of Action
Dydrogesterone is a progestogen structurally related to progesterone. However, unlike progesterone, it does not induce an increase in temp nor inhibit ovulation and may be preferred over other progestational agents when contraceptive effect is not required. It does not have oestrogenic or androgenic properties.
Precaution
Monitor closely for loss of vision, proptosis, diplopia, migraine, signs and symptoms of embolic disorders. CVD or renal impairment, epilepsy, asthma, other conditions which may be aggravated by fluid retention. Lactation.
Side Effect
Dizziness, nausea, headache, fatigue, emotional lability, irritability; abdominal pain and distention; muskuloskeletal pain.
Interaction
Carbamazepine, griseofulvin, phenobarbital, rifampicin enhances the clearance of progestogens.
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