Duzela 20 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Duzela 20 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Duzela 20 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Duzela 20 should be used with caution in patients with severe kidney disease. Dose adjustment of Duzela 20 may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.
UNSAFE
Duzela 20 is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Medicine Overview of Duzela 20mg Capsule
Introduction
Duzela 20 is a prescription medicine used in the treatment of depression, anxiety disorder, diabetic nerve pain, fibromyalgia (a condition in which there are generalized pain and tenderness in the body), neuropathic pain and stress urinary incontinen...
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Uses of Duzela 20
Depression
Anxiety disorder
Diabetic nerve pain
Fibromyalgia
Neuropathic pain
Stress urinary incontinence
Side effects of Duzela 20
Common
Nausea
Headache
Dryness in mouth
Sleepiness
Dizziness
How to use Duzela 20
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duzela 20 may be taken with or without food, but it is better to take it at a fixed time.
How Duzela 20 works
Duzela 20 works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
What if you forget to take Duzela 20?
If you miss a dose of Duzela 20, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Duzela 20 Capsule DR helps in treating depression and anxiety.
It may also be used to treat nerve pain from diabetes and some other forms of chronic pain.
It may take 2 to 4 weeks for Duzela 20 Capsule DR to start working. Keep taking it as prescribed.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Duzela 20 Capsule DR as it may cause excessive drowsiness and increase the risk of liver damage.
It may cause an increase in blood pressure, especially during the first month of treatment. Monitor your blood pressure regularly.
It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.
May be taken with or without food. Swallow whole, do not chew/crush.
Adult Dose
Oral
Major Depressive Disorder
Adult: Initially, 20-30 mg bid or 60 mg once daily, then increase dose in increments of 30 mg/day over 1 wk as tolera...
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Child Dose
Generalized Anxiety Disorder
<7 years: Safety and efficacy not established
7-17 years: 30 mg PO qDay initially; after 2 weeks, may consider increasi...
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Renal Dose
Renal Impairment
Avoid use in patients with severe renal impairment (GFR <30 mL/min)
Contraindication
Duloxetine is contraindicated in patients with a known hypersensitivity to this drug or any of the inactive ingredients.. Uncontrolled narrow-angle gl...
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Mode of Action
Duloxetine is a potent inhibitor of neuronal reuptake of serotonin, norepinephrine and to a lesser extent dopamine. It has no significant affinity for...
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Precaution
Avoid alcohol and abrupt cessation. May impair ability to drive or engage in task requiring alertness. Increased risk of suicidal thinking and behavio...
Pregnancy
There are no adequate and well-controlled studies administration in pregnant women
Use in pregnancy only if the potential benefit justifie...
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Interaction
Increased risk of serotonin syndrome w/ TCA, SSRI, SNRI, lithium. May increase bleeding risk w/ aspirin, NSAIDs, warfarin and other anticoagulants.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.