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Efdinir
Incepta Pharmaceuticals Ltd.
Generic: Cefdinir
Safety Advices
বাংলা
English
UNSAFE
Efdinir may cause excessive drowsiness with alcohol.
SAFE IF PRESCRIBED
Efdinir is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Efdinir is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Avoid prolonged use of Efdinir, since it may have possible effects such as rash and diarrhea.
UNSAFE
Efdinir may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Efdinir should be used with caution in patients with kidney disease. Dose adjustment of Efdinir may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Efdinir is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Efdinir may not be needed in these patients. Please consult your doctor.
Medicine Overview of Efdinir 125mg/5ml Powder for Suspension
Introduction
Efdinir is an antibiotic medicine used to treat a variety of bacterial infections. It is effective in infections of the respiratory tract (eg. pneumonia), urinary tract, ear, nasal sinus, throat, and some sexually transmitted diseases. Efdinir may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed...
... Show moreUses of Efdinir
- Bacterial infections
Side effects of Efdinir
Common
- Rash
- Allergic reaction
- Nausea
- Diarrhea
How to use Efdinir
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Efdinir may be taken with or without food, but it is better to take it at a fixed time.
How Efdinir works
Efdinir is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
What if you forget to take Efdinir?
If you miss a dose of Efdinir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Efdinir to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
- Discontinue Efdinir and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
- Take it with food to avoid an upset stomach.
- Avoid consuming alcohol while taking Efdinir as it may cause increased side effects.
Brief Description
Indication
Community-acquired pneumonia, Susceptible infections, Sinusitis, Otitis media, Sore throat, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis, Acute Maxillary Sinusitis
Administration
May be taken with or without food.
Adult Dose
Community-Acquired Pneumonia, Skin/Skin Structure Infections
300 mg PO q12hr for 10 days
Respiratory Tract Infections, Acute Maxillary Sinusitis
300 mg PO q12hr or 600 mg PO q24hr for 10 days
Hepatic impairment
No dosage adjustment necessary
Child Dose
12 years or >43 kg: 300 mg PO q12hr or 600 mg PO q24hr for 10 days
Renal Dose
Renal impairment:
CrCl (ml/min)
<30 300 mg once daily.
Contraindication
Hypersensitivity.
Mode of Action
Cefdinir binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Precaution
Penicillin-sensitive patients; superinfection; seizure; pseudomembranous colitis; pregnancy, lactation; renal or hepatic insufficiency.
Lactation: Unknown whether drug is excreted in milk
Side Effect
>10%
Diarrhea (8-15%)
1-10%
Vaginal moniliasis (<4%),Nausea (3%),Rash (3%),Headache (2%),Increased urine leukocytes (2%),Increased urine protein (1-2%),Decreased lymphocytes (1%),Glycosuria (1%),Increased alkaline phosphatase (1%),Increased eosinophils (1%),Increased platelets (1%)
Potentially Fatal: Anaphylaxis; renal and hepatic failure.
Pregnancy Category Note
Pregnancy category: B
Lactation: Unknown whether drug is excreted in milk
Interaction
Concomitant admin w/ antacids or Fe supplements reduce the rate and extent of absorption. Admin w/ Fe supplements may cause reddish stools. Decreased renal elimination w/ probenecid.
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