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Sympres 0.3
Eskayef Pharmaceuticals Ltd.
Generic: Moxonidine
Safety Advices
বাংলা
English
UNSAFE
Sympres 0.3 may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Sympres 0.3 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Sympres 0.3 during breastfeeding is not available. Please consult your doctor.
UNSAFE
Sympres 0.3 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Sympres 0.3 should be used with caution in patients with kidney disease. Dose adjustment of Sympres 0.3 may be needed. Please consult your doctor.
CAUTION
Sympres 0.3 should be used with caution in patients with severe liver disease. Dose adjustment of Sympres 0.3 may be needed. Please consult your doctor.
Use of Sympres 0.3 is not recommended in these patients.
Medicine Overview of Sympres 0.3 0.3mg tablet
Introduction
Sympres 0.3 is a medicine used in the treatment of hypertension (high blood pressure). It lowers the blood pressure by relaxing the blood vessels. Lowering the blood pressure helps to prevent future stroke and heart attack. Sympres 0.3 can be taken with or without food. You can take it at any time of day but try to take it at the same time each day. You should take this medicine as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this...
... Show moreUses of Sympres 0.3
- Hypertension (high blood pressure)
Side effects of Sympres 0.3
Common
- Dryness in mouth
- Headache
- Rash
- Dizziness
- Back pain
- Insomnia (difficulty in sleeping)
- Sleepiness
- Vomiting
- Weakness
- Nausea
- Diarrhea
- Vertigo
How to use Sympres 0.3
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sympres 0.3 may be taken with or without food, but it is better to take it at a fixed time.
How Sympres 0.3 works
Sympres 0.3 is an anti-hypertensive medication. It works by relaxing blood vessels which makes the heart more efficient at pumping blood around the body.
What if you forget to take Sympres 0.3?
If you miss a dose of Sympres 0.3, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Sympres 0.3 lowers your blood pressure and makes it easier for your heart to pump blood around your body.
- Lowering high blood pressure helps prevent stroke and heart attack.
- Eat healthy (low-sodium diet), exercise, quit smoking, limit alcohol intake, and reduce stress along with taking Sympres 0.3.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Sympres 0.3 may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- It may cause you to feel lightheaded especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
Brief Description
Indication
Hypertension
Administration
May be taken with or without food.
Adult Dose
Oral
Hypertension
Adult: 200 mcg once daily, increase if necessary after 3 wk to 400 mcg daily as single or in 2 divided doses. If necessary, after a further 3 wk, increase to 600 mcg daily in 2 divided doses. Max: 600 mcg daily.
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
30-60 Single dose should not exceed 200 mcg. Max daily dose 400 mcg.
<30 Avoid
Contraindication
Conduction disorders; bradycardia; severe arrhythmias; severe heart failure; severe ischaemic heart disease; history of angioedema; severe liver or renal impairment; Raynaud's syndrome; intermittent claudication; epilepsy; depression; Parkinson's disease; glaucoma. Pregnancy and lactation.
Mode of Action
Moxonidine is a centrally-acting antihypertensive. It acts in the brainstem through stimulation of central imidazoline receptors to reduce sympathetic tone. Moxonidine also has a low affinity for alpha2-adrenoceptors.
Precaution
Renal impairment; avoid abrupt withdrawal (if concomitant treatment with ?-blocker has to be stopped, discontinue ?-blocker first, then moxonidine after few days).
Side Effect
Dry mouth; headache; fatigue; dizziness; nausea; sleep disturbances; asthenia; vasodilatation; skin reactions; constipation; depression; anxiety; anorexia; parotid pain; vivid dreams; impotence and loss of libido; urinary retention or incontinence; slight orthostastic hypotension; fluid retention.
Interaction
Additive effects with other antihypertensives; may increase sedative effects of benzodiazepines. Effects may be antagonised by TCAs.
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