12-24 Hours
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Kinate 50
Ziska Pharmaceuticals Ltd.
Generic: Itopride Hydrochloride
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Itopride Hydrochloride. Please consult your doctor.
CONSULT YOUR DOCTOR
Safety of itopride in pregnancy was not verified. Therefore itopride can be used in pregnant women or women in that pregnancy cannot be excluded only if therapeutic benefits outweigh possible risks considerably.
UNSAFE
Data about excretion in mother milk is known only in animals. Because of lack of experience with use of itopride during breast-feeding itopride it is not recommended for breast-feeding women.
CONSULT YOUR DOCTOR
It is not known whether Itopride Hydrochloride alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
SAFE IF PRESCRIBED
Itopride Hydrochloride is safe to use in patients with kidney disease. Dose adjustment of Itopride Hydrochloride is recommended.
CAUTION
Itopride Hydrochloride should be used with caution in patients with severe liver disease. Dose adjustment of Itopride Hydrochloride may be needed. If abnormalities occur, the drug should be discontinued and appropriate therapeutic measures implemented.
Medicine Overview of Kinate 50mg tablet
Administration
The usual adult dose for oral use is 50 mg of Itopride Hydrochloride administered orally three times daily. The dose may be reduced according to the patient’s age and symptoms. Itopride Hydrochloride should be taken before meals.
Dosage
The usual adult dose for oral use is 50 mg of Itopride Hydrochloride administered orally three times daily. The dose may be reduced according to the patient’s age and symptoms. Itopride Hydrochloride should be taken before meals. Use in the elderly: Since the elderly often have a physiological hypo function, they are prone to adverse reactions and should thus be closely monitored. If adverse reactions are evident, appropriate measures such as reduction or cessation of the drug should be implemented. Use in pediatric population: The safety and efficacy of Itopride Hydrochloride in children and adolescents have not been established. Therefore,...
... Show moreInteraction
Itopride Hydrochloride should be administered with care when co-administered with the following drugs: Anticholinergic Drugs, Tiquizium bromide, Scopolamine butyl bromide, Timepidium bromide, etc. Sign: There is a possibility of reducing the activity of Itopride Hydrochloride which activates gastrointestinal motility (cholinergic action). Mechanism & risc factor: Gastrointestinal motility inhibitory action of Anticholinergic pharmacologically decreases the activity of the drug.
Contraindications
Hypersensitivity to the active substance or to any of the excipients onthis preparation. This should not be used in patients in whom increased gastrointestinal motility could be harmful, e.g. in patients with gastrointestinal haemorrhage, mechanical obstruction or perforation.
Precautions & Warnings
Important Precautions: This drug should be used with caution since it enhances the action of acetylcholine. This drug should not be consumed continuously for an extended period when no improvement of gastrointestinal symptoms is observed. Precautions concerning Use: When granting agent: For drugs packaged in a press-through package (PTP), instruct the patient to remove the drug from the package prior to ingestion. (It has been reported that, by accidental ingestion of the PTP sheet, the hard and sharp corners may puncture the esophageal mucosa, or even lead to perforation resulting in serious complications such as mediastinal sinusitis.)
Overdose Effects
In case of excessive overdose, the usual measures of gastric lavage and symptomatic therapy should be applied.
Storage Conditions
Store below 30°C, in a cool and dry place. Keep away from light. Keep all the medicine out of the reach of children.
Brief Description
Indications
Gastrointestinal symptoms in chronic gastritis (feeling of an enlarged abdomen, upper abdominal pain, anorexia, heartburn, nausea and vomiting).
Pharmacology
Itopride Hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase inhibitor. It increases acetylcholine concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Higher acetylcholine increases Gl peristalsis, increases the lower esophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination.
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