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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Eplon.
CONSULT YOUR DOCTOR
Eplon may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Eplon is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Eplon may cause side effects which could affect your ability to drive.
CAUTION
Eplon should be used with caution in patients with severe kidney disease. Dose adjustment of Eplon may be needed. Please consult your doctor.
Limited information is available on the use of Eplon in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
CAUTION
Eplon should be used with caution in patients with liver disease. Dose adjustment of Eplon may be needed. Please consult your doctor.
Use of Eplon is not recommended in patients with severe liver disease.
Medicine Overview of Eplon 5mg Capsule
Introduction
Eplon is a prescription medicine used to treat insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep. Eplon should be taken on an empty stomach, preferably before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit forming. Do not stop taking it suddenly without talking to your doctor as it may...
... Show moreUses of Eplon
- Insomnia
Side effects of Eplon
Common
- Dizziness
- Lightheadedness
- Impaired coordination
- Paresthesia (tingling or pricking sensation)
How to use Eplon
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Eplon is to be taken empty stomach.
How Eplon works
Eplon is a nonbenzodiazepine hypnotic. Along with sedative, it may also have anxiolytic (panic-reducing or antianxiety), muscle relaxant properties. It works by binding GABA-A/chloride ion channel receptor complex (receptor), thus relaxes the nerves and brain. This is how it helps you to fall asleep.
What if you forget to take Eplon?
If you miss a dose of Eplon, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Eplon to help you fall asleep faster and sleep for longer.
- It is best taken without food as a high-fat meal can reduce its absorption and effect.
- Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
- It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
- It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night.
- Never share your medication with any other person who also has a sleep problem.
- Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
- Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
- Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.
Brief Description
Indication
Insomnia
Administration
May be taken with or without food. Do not take w/ or immediately after a heavy or high fat meal.
Adult Dose
Oral
Insomnia
Adult: 5-10 mg before bedtime. Max: 20 mg daily.
Elderly: >65 yr: 5 mg before bedtime. Max: 10 mg daily.
Hepatic impairment: Mild to moderate: 5 mg at bedtime. Severe: Contra-indicated.
Child Dose
Not recommended
Renal Dose
Renal Impairment
Mild to moderate impairmet: No dose adjustment necessary
Severe impairment: Not studied
Contraindication
Hypersensitivity. Severe hepatic impairment. Lactation.
Mode of Action
Zaleplon, a pyrazolopyrimidine, is a sedative and hypnotic agent structurally unrelated to the benzodiazepines and other sedative-hypnotic agents. It is shown to interact with GABA subtype A complex by binding selectively to benzodiazepine type 1 receptor. It reduces sleep latency without affecting sleep duration.
Precaution
May precipitate new psychiatric abnormalities. Depression; hepatic impairment. History of drug or alcohol dependence or abuse, elderly and debilitated patients. Childn <18 yr. Pregnancy. May impair ability to drive or operate machinery. Do not take zaleplon if there is <4 hr of sleep. Dose reduction or withdrawal of drug should be done gradually.
Side Effect
>10%
Headache (38%)
1-10%
Dizziness (7-9%),Nausea (6-8%),Abdominal pain (6%),Weakness (5-7%),Dysmenorrhea (3-4%),Eye pain (3-4%),Amnesia (2-4%),Parasthesia (3%),Tremor (2%)
<1%
Fever,Photosensitivity,Anorexia,Colitis,Periphipheral edema,Amnesia,Anxiety,Depersonalization,Hallucination,Hypesthesia,Vertigo,Epistaxis,Abnl vision,Ear pain,Hyperacusis,Parosmia
Interaction
Additive CNS effects may occur with CNS depressants e.g. TCA, alcohol, antihistamines, narcotic analgesics, thioridazine and diphenhydramine. Cytochrome P450 CYP3A4 inducers e.g. rifampicin, phenytoin, carbamazepine and phenobarbital decrease zaleplon concentrations. Increased zaleplon concentration with cimetidine and CYP 3A4 inhibitors e.g. erythromycin, ketoconazole.
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