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Minocin 50
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Minocycline
Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Minocin 50. Please consult your doctor.
CONSULT YOUR DOCTOR
Minocin 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Minocin 50 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Minocin 50 may cause side effects which could affect your ability to drive.
Minocin 50 can cause lightheadedness, visual disturbances, dizziness, ringing in the ears, a feeling of dizziness or spinning (vertigo). This may affect your driving ability.
CAUTION
Minocin 50 should be used with caution in patients with severe kidney disease. Dose adjustment of Minocin 50 may be needed. Please consult your doctor.
CAUTION
Minocin 50 should be used with caution in patients with liver disease. Dose adjustment of Minocin 50 may be needed. Please consult your doctor.
Medicine Overview of Minocin 50mg tablet
Introduction
Minocin 50 is an antibiotic medicine used to treat bacterial infections in your body. It is effective in some infections of the lungs, urinary tract, eyes, and others. It kills bacteria, which helps to improve your symptoms and cure the infection. Minocin 50 is also used to treat many sexually transmitted diseases and a skin condition known as acne. It may be taken with or without food. However, you should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take...
... Show moreUses of Minocin 50
- Bacterial infections
Side effects of Minocin 50
Common
- Headache
- Dizziness
- Photosensitivity
- Vomiting
- Nausea
- Itching
- Diarrhea
How to use Minocin 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Minocin 50 may be taken with or without food, but it is better to take it at a fixed time.
How Minocin 50 works
Minocin 50 is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.
Quick Tips
- Your doctor has prescribed Minoz OD 100 Capsule MR to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Minoz OD 100 Capsule MR affects you.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Discontinue Minoz OD 100 Capsule MR and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Brief Description
Indication
Susceptible infections, Acne, Asymptomatic meningococcal carriers, Uncomplicated gonorrhoea, Nongonococcal urethritis, Syphilis,
Administration
IV Preparation Reconstitute cryodessicated powder with 5 mL sterile water for injection Immediately dilute further with 500-1000 mL of 0.9% NaCl, dextrose solutions, dextrose and NaCl solutions, Ringer Injection, or Lactated Ringer Reformulated Minocin IV Allows for dilution with lower fluid volume After vial reconstitution, dilute further with 100-1000 mL of 0.9% NaCl, dextrose solutions, dextrose and NaCl solutions, or 250-1000 mL of Ringer or Lactated Ringer injections IV Administration Avoid rapid IV infusion Infuse over one hour Not to exceed 400mg in 24 hours Oral Administration May take with or without food Ingestion of food along with may help...
... Show moreAdult Dose
Oral Susceptible infections Adult: 200 mg daily in divided doses. Acne Adult: 50 mg bid or 100 mg once daily. ?45 kg: 1 mg/kg once daily as modified-release preparation. Asymptomatic meningococcal carriers Adult: 100 mg bid for 5 days, followed by a course of rifampicin. Nongonococcal urethritis Adult: 100 mg 12 hrly for at least 7 days. Uncomplicated gonorrhoea Adult: Initially, 200 mg, followed by 100 mg 12 hrly for a min of 4 days, follow-up cultures should be done w/in 2-3 days after completion of therapy. Uncomplicated urethral gonorrhoea in men Adult: 100 mg 12 hrly for 5 days....
... Show moreChild Dose
Intravenous
Susceptible infections
Child: >8 yr Initially, 4 mg/kg, then 2 mg/kg 12 hrly not to exceed the usual adult dose.
Oral
Acne Vulgaris
<12 years: Safety and efficacy not established
Immediate-release products: 4 mg/kg PO initially (not to exceed 200 mg), THEN 2 mg/kg/day PO q12hr; not to exceed 400 mg/day
Extended-release tablets: 1 mg/kg PO qDay
Administer therapy for 12 weeks
Renal Dose
Renal impairment: Reduce dose or increase dosing interval. Max: 200 mg/day.
Contraindication
Documented hypersensitivity
Mode of Action
Minocycline inhibits protein synthesis by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria. It is active against Streptococcus aureus, Neisseria meningitidis, various enterobacteria, Acinetobacter, Bacteroides, Haemophilus and Nocardia spp., and some mycobacteria.
Precaution
Caution in significant renal impairment (may lead to azotemia, hyperphosphatemia, and acidosis; monitor BUN) Adjust dose if renal impairment occurs Anaphylaxis reported; discontinue use and institute supportive therapy Prolonged use may result in fungal or bacterial superinfection Lupus, hepatitis, and vasculitis autoimmune syndromes reported with use; discontinue if lupus symptoms occur and assess liver function tests; ANA and CBC Discontinue therapy if pseudomembranous colitis occurs Risk of vestibular reactions Caution in hepatic impairment; discontinue if liver injury occurs Photosensitivity may occur with prolonged exposure to sunlight or tanning equipment; use skin protection and avoid prolonged exposure to sunlight Reduce dose...
... Show moreSide Effect
Discoloration of teeth (in children)
Vestibular symptoms (>30%)
Pericarditis
Myocarditis
Vasculitis
Angioedema
Alopecia
Erythema nodosum
Erythematous rash
Exfoliative dermatitis
Pruritus
Toxic epidermal necrolysis
Urticaria
Dizziness
Fever
Fatigue
Somnolence
Angioedema
Hyperpigmentation of nails
Pigmentation of skin and mucous membranes
Thyroid dysfunction
Thyroid discoloration
Thyroid cancer
Vulvovaginitis
Hemolytic anemia
Neutropenia
Thrombocytopenia
Agrunolocytosis
Pancytopenia
Hepatic cholestasis
Hepatitis
Hyperbilirubinemia
Jaundice
CNS effects
Clostridium difficile diarrhea
Pregnancy Category Note
Pregnancy category: D
Lactation: Enters breast milk, some manufacturers say do not nurse; however AAP considers nursing compatible due to calcium chelation of drug and prevention of its absorption; long-term safety of prolonged exposure unknown
Interaction
Impaired absorption by concomitant admin w/ Ca-containing antacids and other divalent or trivalent cations (e.g. Al, bismuth, Fe, Mg, Zn). May decrease effectiveness of oral contraceptives. May interfere w/ the bactericidal action of penicillins. May potentiate the effect of anticoagulants. Increased risk of nephrotoxicity w/ diuretics. Increased risk of pseudotumour cerebri w/ retinoids (e.g. isotretinoin). Increased risk of ergotism w/ ergot alkaloids.
Potentially Fatal: Concurrent use w/ methoxyflurane may result to fatal renal toxicity.
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