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Feverein
General Pharmaceuticals Ltd.
Generic: Nimesulide
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Feverein.
CONSULT YOUR DOCTOR
Feverein is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Feverein during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
It is not known whether Feverein alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Feverein should be used with caution in patients with kidney disease. Dose adjustment of Feverein may be needed. Please consult your doctor.
Use of Feverein is not recommended in patients with severe kidney disease.
UNSAFE
Feverein is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Medicine Overview of Feverein 100mg Tablet
Introduction
Feverein is a pain relieving medicine. It is used for treatment of inflammatory condition including joint disorders such as rheumatoid arthritis, postoperative painful condition, fever, and period pain. Feverein should be taken with food. This will prevent you from getting an upset stomach. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective. Some common side effects of this medicine includes diarrhea, nausea, and vomiting. If any...
... Show moreUses of Feverein
- Pain relief
- Fever
Side effects of Feverein
Common
- Vomiting
- Nausea
- Diarrhea
How to use Feverein
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Feverein is to be taken with food.
How Feverein works
Feverein is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
What if you forget to take Feverein?
If you miss a dose of Feverein, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Feverein is used to relieve pain, inflammation, and fever.
- Take it with food or milk to prevent upset stomach.
- Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Avoid consuming alcohol while taking Feverein as it can increase your risk of stomach problems.
- Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Brief Description
Indication
Acute pain, Extra-articular disorders, Osteoarthritis, Post-op pain, Primary dysmenorrhoea
Administration
Should be taken with food. Take after meals.
Adult Dose
Oral
Acute pain; Dysmenorrhoea; Osteoarthritis; Postoperative pain
Adult: 100 mg bid. Use max of 15 days.
Contraindication
Hypersensitivity; GI bleeding, active peptic ulcer disease; severe renal and heart failure; hepatic impairment or known liver disease; coagulation disorders; pregnancy; children <12 yr.
Mode of Action
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, anti-pyretic, and analgesic properties. It inhibits prostaglandin synthetase/cyclooxygenase, which limits prostaglandin production. Its cyclooxygenase inhibiting potency is intermediate, but is relatively selective for the cyclo-oxygenase-2 (COX-2) thus the potential for gastric injury and intolerance is less. It is also a free radical scavenger, and helps protect against the tissue damage that occurs during inflammation.
Precaution
History of GI tract disease, infections, oedema, hypertension, elderly, lactation.
Side Effect
Epigastric discomfort, heartburn or abdominal cramps, nausea, vomiting and diarrhoea; skin rash, pruritus, oedema, headache, dizziness, drowsiness; hypersensitivity reactions (e.g. bronchospasm, rhinitis, angioedema urticaria); GI haemorrhage/perforation; bullous/erosive stomatitis, purpura, thrombocytopenia, toxic epidermal necrolysis, haematuria, oliguria, and renal failure; increases in liver enzymes.
Potentially Fatal: Fatal hepatitis, Stevens Johnson syndrome.
Interaction
Additive hepatotoxic effects with known hepatotoxins: anti-convulsants (e.g. valproic acid), anti-fungals (e.g. ketoconazole), anti-tuberculous drugs (e.g. isoniazid), tacrine, pemoline, amiodarone, methotrexate, methyldopa, amoxicillin/clavulanic acid. May decrease the oral bioavailability of furosemide and the natriuretic and diuretic response to furosemide. Increased risks of GI and hepatic adverse effects with other NSAIDs, including aspirin. May increase anti-coagulant effect of warfarin. Potentiates the action of phenytoin. May be displaced from binding sites with fenofibrate, salicylic acid, and tolbutamide. Interactions between NSAIDs and lithium, probenecid and ciclosporin, have been documented.
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