Firifam 300 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Firifam 300 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Firifam 300 may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
CAUTION
Firifam 300 should be used with caution in patients with kidney disease. Dose adjustment of Firifam 300 may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Firifam 300 in patients with liver disease. Please consult your doctor.
Medicine Overview of Firifam 300mg Tablet
Introduction
Firifam 300 is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. It may be used alone or in combination with other medicines to fight seri...
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Uses of Firifam 300
Tuberculosis (TB)
Side effects of Firifam 300
Common
Low blood platelets
Headache
Dizziness
Vomiting
Abnormal liver function tests
Nausea
Fever
Chills
How to use Firifam 300
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Firifam 300 is to be taken empty stomach.
How Firifam 300 works
Firifam 300 is an antibiotic. It works by inactivating a bacterial enzyme (RNA-polymerase) which is required by bacteria to make essential proteins and to reproduce.
What if you forget to take Firifam 300?
If you miss a dose of Firifam 300, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Your doctor has prescribed Firifam 300 to cure your infection and improve symptoms.
It is best taken on an empty stomach. If you get an upset stomach, try taking it with small portions of food.
Your urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored.
Tell your doctor about all other medicines you are taking as Firifam 300 can interact with many medicines.
Avoid taking hormone-based birth control methods as Firifam 300 may decrease their effectiveness.
Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.
Oral
Tuberculosis
10–20 mg/kg, max 600 mg for TB q24h
With directly observed biweekly therapy, dosage is still 10–20 mg/kg/dose (max 600 mg) twice ...
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Contraindication
Hypersensitivity to rifampicin or other rifamycins. Patient w/ jaundice. Concurrent use w/ saquinavir/ritonavir therapy.
Mode of Action
Rifampicin suppresses initiation of chain formation for RNA synthesis in susceptible bacteria by binding to the beta subunit of DNA-dependent RNA poly...
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Precaution
Patient w/ history of alcoholism. Hepatic and renal impairment. Elderly, malnourished patients, childn <2 yr. Pregnancy and lactation. Patient Counsel...
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Side Effect
Facial flushing and itching, w/ or w/o a rash, flu-like syndrome characterised by episodes of fever, chills, headache, dizziness, bone pain, shortness...
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Interaction
May accelerate the metabolism and reduce the effect of drugs that are metabolised by CYP450 enzymes (e.g. quinidine, phenytoin, theophylline). Decreas...
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.