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Avaxim Pediatric
Synovia Pharma PLC.
Generic: Hepatitis A Virus (Inactivated) Vaccine
Medicine Overview of Avaxim Pediatric 80unit/0.5 ml injection
বাংলা
English
Indication
Active immunization against Hepatitis A virus.
Hepatitis A vaccine is used to prevent, hepatitis A
Administration
Hepatitis A vaccine should be given intramuscularly only.
Adult Dose
Intramuscular
Active immunisation against hepatitis A
Adult:
First dose: At selected date
Second dose: 6 months after first dose
Child Dose
Intramuscular
Active immunisation against hepatitis A
Children of 1 year of age
First dose: At selected date
Second dose: 6 months after first dose
Children 12 months to 15 years: The recommended dose is 0.5 ml
First dose: At selected date
Second dose: 6 months after first dose
Children 16 years and above: The recommended dose is 1 ml
First dose: At elected date
Second dose: 6 months after first dose
Contraindication
Hypersensitivity. Vaccines prepared in egg cultures are contraindicated in patients with hypersensitivity reactions to egg. Severe immunodeficiency. Malignant disease being treated with chemotherapy or radiotherapy and for at least 6 mth after stopping treatment. Patients with compromised immune system such as those on high-dose systemic corticosteroids, immunosuppressants or HIV positive.
Mode of Action
Hepatitis A antigen is prepared from formaldehyde-inactivated hepatitis A virus grown in human diploid cells. It is used for active immunisation against hepatitis A infection.
Precaution
Alcohol or disinfectant used for cleaning the skin prior to inj should be allowed to evaporate completely before vaccination to prevent vaccine inactivation.
The vaccine should be given to a pregnant woman only if clearly needed.
Lactation: not established
Side Effect
>10%
Injection site tenderness (3-56%), erythema (1-22%), warmth (1-17%), swelling (9-11%),Irritability (11-36%),Anorexia (1-19%),Drowsiness (15-17%),Headache (1-16%),Fever > 100.4 F (9-11%)
1-10%
URI (1-10%),Otitis media (8%),Rhinorrhea (6%),Diarrhea (1-6%),Cough (1-5%),Rash (1-5%),Weakness/fatigue (4%),Vomiting (1-4%),Fever > 102 F (3%),Crying (2%)
<1%
Hematoma,Incr. CPK,Photophobia,Vertigo
Potentially Fatal: Anaphylaxis.
Interaction
Reduced response to vaccination when used concurrently with immunosuppressants such as corticosteroids or antineoplastics.
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