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Buflex 1000

tablet-(1000mg)
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Beximco Pharmaceuticals Ltd.

Generic: Nabumetone

10 Tablets (1 Strip)
৳ 270
৳ 300
10% OFF
Alternative Brands For Buflex 1000

Medicine Overview of Buflex 1000mg tablet

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Introduction

Buflex 1000 is a pain relieving medicine. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis and osteoarthritis. Buflex 1000 should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke. Vomiting, stomach pain, nausea and indigestion are some of the common side effects that might be observed on taking this medicine. It may also cause dizziness, drowsiness or visual disturbances. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment. Long term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses of Buflex 1000

  • Pain relief

Side effects of Buflex 1000

Common
  • Vomiting
  • Stomach pain/epigastric pain
  • Nausea
  • Indigestion
  • Loss of appetite
  • Diarrhea
  • Heartburn

How to use Buflex 1000

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Buflex 1000 is to be taken with food.

How Buflex 1000 works

Buflex 1000 is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Quick Tips

  • You have been prescribed Buflex 1000 to relieve pain and inflammation.
  • Take it with food or milk to prevent upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
  • Avoid consuming alcohol while taking Buflex 1000 as it can cause excessive drowsiness and increase your risk of stomach problems.
  • Inform your doctor if you have a history of heart disease or stroke.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Brief Description

Indication

Pain and inflammation associated with musculoskeletal and joint disorders, Osteoarthritis, Rheumatoid Arthritis

Administration

Should taken with food.

Adult Dose

Oral Adult Osteoarthritis 1g PO once daily initially; maintenance: 1-2 g/day PO in single daily dose or divided q12hr; not to exceed 2 g/day Rheumatoid Arthritis 1 g PO once daily initially; maintenance: 1-2 g/day PO in single daily dose or divided q12hr; not to exceed 2 g/day Elderly: 500 mg daily may be adequate in certain patients. Max: 1 g daily.

Child Dose

Not recommended

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation 30-49 Max initial dose: 750 mg once daily. Increase if needed to a max dose of 1.5 g daily. <30 Max initial dose: 500 mg once daily. Increase if needed to a max dose of 1 g daily.

Contraindication

Absolute: Aspirin allergy, severe renal impairment; perioperative pain in setting of coronary artery bypass graft (CABG) surgery Relative: Duodenal/gastric/peptic ulcer, stomatitis, systemic lupus erythematosus, ulcerative colitis, late pregnancy (may cause premature closure of ductus arteriosus)

Mode of Action

Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclooxygenase (COX) isoenzymes, COX-1 and COX-2 May inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects may contribute to anti-inflammatory activity

Precaution

Pre-existing CV risk factors or disease; fluid retention, CHF, hypertension. History of GI disease (bleeding or ulcers). Elderly or debilitated patients. Other forms of asthma. Hepatic impairment; closely monitor patients with any abnormal LFT. Renal impairment; rehydrate patient prior to therapy and closely monitor renal function. Withhold for at least 4-6 half-lives prior to surgical or dental procedures.

Side Effect

>10% Diarrhea (14%),Dyspepsia (13%),Abdominal pain (12%) 1-10% Constipation (3-9%),Dizziness (3-9%),Edema (3-9%),Flatulence (3-9%),Headache (3-9%),Nausea (3-9%),Positive stool guaiac (3-9%),Pruritus (3-9%),Rash (3-9%),Tinnitus (3-9%),Dry mouth (1-3%),Fatigue (1-3%),Gastritis (1-3%),Increased sweating (1-3%),Insomnia (1-3%),Nervousness (1-3%),Somnolence (1-3%),Stomatitis (1-3%),Vomiting (1-3%)

Pregnancy Category Note

Pregnancy category: C; D if used for prolonged periods or near term (premature closure of ductus arteriosus)

Interaction

Antihypertensive effects of hypotensive agents may be reduced. May increase ciclosporin levels. Increased risk of seizures with fluoroquinolones. May reduce efficacy of diuretics. May diminish the cardioprotective effect of acetylated salicylates. Alcohol may enhance gastric mucosal irritation. Potentially Fatal: Increased risk of bleeding with anticoagulants (e.g. warfarin, heparin, LMWHs) and antiplatelet agents (e.g. ticlopidine, clopidogrel, aspirin, abciximab, dipyridamole, eptifibatide, tirofiban). Increased risk of GI ulceration with corticosteroids. Severe bone marrow suppression, aplastic anaemia and GI toxicity may occur with methotrexate.

Buy Buflex 1000 from Arogga

In Bangladesh, you can get the original Buflex 1000. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Buflex 1000 in Bangladesh?

The latest price of Buflex 1000 in Bangladesh is 270৳. You can buy Buflex 1000 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
It is unsafe to consume alcohol with Buflex 1000.
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CONSULT YOUR DOCTOR
Buflex 1000 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Buflex 1000 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Buflex 1000 may cause side effects which could affect your ability to drive. As may feel dizzy, tired, have problems with your vision or have headaches after taking Buflex 1000 and this may affect your ability to drive.
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CAUTION
Buflex 1000 should be used with caution in patients with kidney disease. Dose adjustment of Buflex 1000 may be needed. Please consult your doctor. Kidney function tests and some other blood tests may advised when you will start with this therapy and then at regular intervals while you are taking this medicine.
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CAUTION
Buflex 1000 should be used with caution in patients with liver disease. Dose adjustment of Buflex 1000 may be needed. Please consult your doctor. Use of Buflex 1000 is not recommended in patients with severe liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.