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Glyset R Penset
Incepta Pharmaceuticals Ltd.
Generic: Insulin Aspart
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Glyset R Penset.
SAFE IF PRESCRIBED
Glyset R Penset is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Glyset R Penset is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION
Glyset R Penset should be used with caution in patients with kidney disease. Dose adjustment of Glyset R Penset may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
CAUTION
Glyset R Penset should be used with caution in patients with liver disease. Dose adjustment of Glyset R Penset may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised.
Medicine Overview of Glyset R Penset 100IU/ml Injection
Introduction
Glyset R Penset is used for the treatment of blood sugar control in people with type 1 and type 2 diabetes mellitus. It is a fast-acting type of insulin that helps to lower blood sugar levels after meals and reduce the chances of developing serious complications of diabetes. Glyset R Penset is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Check your...
... Show moreUses of Glyset R Penset
- Diabetes mellitus (Type 1 & Type 2)
Side effects of Glyset R Penset
Common
- Hypoglycemia (low blood glucose level)
- Lipodystrophy (skin thickening or pits at the injection site)
- Injection site allergic reaction
- Itching
- Rash
How to use Glyset R Penset
Your doctor or nurse will guide you how to use this medicine.
How Glyset R Penset works
Glyset R Penset is fast-acting insulin. It starts working within 10-20 minutes after injection. It works like your body's natural insulin. Insulin facilitates reuptake of glucose in muscles and fat cells and also blocks the release of glucose from the liver.
What if you forget to take Glyset R Penset?
If you have missed a dose of Glyset R Penset, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.
Quick Tips
- Take it 15 minutes before a meal or within 20 minutes after starting a meal.
- Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
- Injection below the skin of the abdomen results in faster absorption than other injection sites.
- Injection sites must be rotated to prevent hard lumps from developing at one site.
- Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
- Do not use it if the preparation is no longer clear and colorless or if it contains particles.
Brief Description
Indication
Diabetes mellitus
Administration
SC injection
Should be taken with food. Administer immediately within 5-10 minutes before a meal.
When administered by SC injection, insulin aspart should generally be used in regimens with an intermediate- or long-acting insulin
Administer subcutaneously in the upper arm, thigh or abdominal wall. A subcutaneous injection into the abdominal wall results in a faster absorption than from other injection sites.
Injection sites should be rotated within the same region to reduce the risk of lipodystrophy
Adult Dose
Subcutaneous Type 1 Diabetes Mellitus Improvement of glycemic control in adults and children with diabetes mellitus May administer 0.2-0.6 unit/kg/day in divided doses; conservative doses of 0.2-0.4 unit/kg/day often recommended to reduce risk of hypoglycemia Total maintenance daily insulin requirement may vary; it is usually between 0.5 and 1 unit/kg/day; nonobese may require 0.4-0.6 unit/kg/day; obese may require 0.6-1.2 units/kg/day Type 2 Diabetes Mellitus Diabetes inadequately controlled by diet, weight reduction, exercise, or oral medication Initial: 0.2-0.4 units/kg/day SC divided q8hr-q12hr. And an intermediate (eg, NPH) or long-acting insulin at bedtime recommended; Hepatic impairment: Dosage reduction may be needed. Dosing...
... Show moreChild Dose
Subcutaneous
Type 1 Diabetes Mellitus
Improvement of glycemic control in adults and children with diabetes mellitus
>2 years: May require 0.8-1.2 units/kg/day SC during growth spurts; adolescents may require <1.2 units/kg/day; otherwise, may use 0.5-1 unit/kg/day
Renal Dose
Renal impairment: Dose adjustments may be needed.
Contraindication
Hypoglycaemia. Hypersensitivity to any of the components.
Mode of Action
Insulin aspart, a rapid-acting analog of human insulin, lowers blood glucose levels; it regulates carbohydrate, protein and fat metabolism by inhibiting hepatic glucose production and lipolysis, and enhancing peripheral glucose disposal.
Precaution
Pregnancy (insulin requirements tend to fall during the 1st trimester, increase during the 2nd and 3rd) and lactation. Caution with decreased insulin requirements: Diarrhea, nausea/vomiting, malabsorption, hypothyroidism, renal impairment, hepatic impairment
Hypokalemia may occur
Use with caution in renal and hepatic impairment (dosage requirements may be reduced)
Caution with increased insulin requirements: Fever, hyperthyroidism, trauma, infection, surgery
Lactation: Safe to use while breastfeeding
Side Effect
Allergic reactions. Injection site reaction, lipodystrophy, pruritus, rash, lipoatrophy, hypokalaemia, blurred vision. Hypoglycaemia, insulin resistance.
Interaction
Effects may be increased by: oral antidiabetic agents, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, propoxyphene, salicylates, somatostatin analog (e.g., octreotide), sulfonamide antibiotics. Effects may be decreased by: corticosteroids, niacin, danazol, diuretics, sympathomimetic agents, isoniazid, phenothiazine derivatives, somatropin, thyroid hormones, oral contraceptives, lithium. Signs of hypoglycaemia may be masked by beta-blockers, clonidine.
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