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Grisofulvin M
Modern Pharmaceuticals Ltd.
Generic: Griseofulvin
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Grisofulvin M.
UNSAFE
Grisofulvin M is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
CONSULT YOUR DOCTOR
Grisofulvin M is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Grisofulvin M may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Grisofulvin M is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grisofulvin M may not be needed in these patients. Please consult your doctor.
Regular monitoring of kidney function test may be advised while you are taking this medicine.
CAUTION
Grisofulvin M should be used with caution in patients with liver disease. Dose adjustment of Grisofulvin M may be needed. Please consult your doctor.
Use of Grisofulvin M is not recommended in patients with severe liver disease. Regular monitoring of liver function test may be advised while the patient is taking this medicine.
Medicine Overview of Grisofulvin M 500mg Tablet
Introduction
Grisofulvin M is an antifungal medication. It is used to treat fungal infections of the skin, nails, scalp, or hair. This medicine is usually used when other medicines failed to clear up the infection or are not appropriate. It kills the fungus and prevents it from growing on your skin. Grisofulvin M should be taken with food. This will help your body to absorb the medicine. Take it regularly and at the same time each day. Follow the doctor's instructions carefully to get the most benefit. You should not stop taking this medicine without consulting your doctor. Some common side...
... Show moreUses of Grisofulvin M
- Fungal infections
Side effects of Grisofulvin M
Common
- Headache
- Skin rash
- Nausea
- Diarrhea
- Dizziness
How to use Grisofulvin M
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grisofulvin M is to be taken with food.
How Grisofulvin M works
Grisofulvin M is an antifungal medication. It stops the growth of fungi by preventing fungal cell division.
Quick Tips
- Grisofulvin M is used to treat fungal infections of the skin, nails, scalp or hair, when other medicines have failed to clear up the infection or are not appropriate.
- Take it with food to help your body absorb the medicine.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- Use caution while driving or doing anything that requires concentration as Grisofulvin M may cause dizziness.
- Avoid consuming alcohol when taking Grisofulvin M as it may cause excessive drowsiness, nausea, vomiting, and headaches.
- It can make you more sensitive to sunlight. Wear sunscreen and protective clothing when outdoors.
- It can make birth control pills less effective. Use an additional method of contraception while taking Grisofulvin M.
- Do not take Grisofulvin M if you are pregnant or breastfeeding.
Brief Description
Indication
Dermatophytosis
Administration
Should be taken with food. Take immediately after meals.
Adult Dose
Oral
Dermatophytosis
Adult: 0.5-1 g daily in single or divided doses.
Treatment duration: 2-8 wk (hair and skin infections); up to 6 mth (fingernail infections); >12 mth (toenail infections).
Child Dose
Oral
Dermatophytosis
Child: PO 20–25 mg/kg q24h
Contraindication
Severe liver disease; porphyria; monilial infection; SLE; pregnancy.
Mode of Action
Griseofulvin is a fungistatic antibiotic that inhibits fungal cell division at metaphase and binds to human keratin making it resistant to fungal infections. It has activity against common dermatophytes including epidermophyton, Microsporum, or Trichophyton spp.
Precaution
Lactation; may impair ability to drive or operate machinery; avoid exposure to intense sunlight or artificial light. Regular monitoring of the renal, hepatic and blood tests should be done.
Lactation: Excretion in milk unknown; avoid use because of potential tumorigenicity
Side Effect
Oral thrush; GI distress, taste perversion; dizziness, confusion, headache, depression, insomnia, fatigue; peripheral neuritis, photosensitivity; skin rashes, urticaria, erythema multiforme; leucopenia, proteinuria.
Potentially Fatal: Hepatotoxicity; angioedema.
Interaction
Antagonises oral anticoagulants and oral contraceptives. Decreased GI absorption with phenobarbital. Reduced plasma concentrations with enzyme inducers e.g. phenylbutazone and hypnotics.
Potentially Fatal: Enhances effects of alcohol and causes disulfiram-like reaction.
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