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Imilast 500

Injection-(500mg+500mg)
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Biopharma Ltd.chevron-right

Generic: Imipenem + Cilastatin

Stock AvailableStock: Available
1 Injection
৳1086.26
৳1195
9% OFF

Medicine Overview of Imilast 500mg+500mg Injection

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Introduction

Imilast 500 is a combination of antibiotic medicines. It is prescribed to treat various types of severe bacterial infections. It fights against the infection-causing microorganisms to prevent further infections. Imilast 500 should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better. The common side effects of this medicine are nausea, vomiting, diarrhea, rashes, etc. You may also experience injection site redness, swelling, and pain that goes away with time. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help. Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy.

Uses of Imilast 500

  • Severe bacterial infections

Side effects of Imilast 500

Common
  • Nausea
  • Vomiting
  • Diarrhea
  • Rash

How to use Imilast 500

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Imilast 500 works

Imilast 500 is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem. Hence, it helps Imipenem stay active in your body for a longer period of time.

Quick Tips

  • Imilast 500 is used to treat severe bacterial infections, including those acquired in hospital and those involving many different types of bacteria.
  • It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
  • Tell you doctor if you are allergic to penicillin as this medicine should be avoided or used with caution in penicillin allergy.
  • Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Brief Description

Indication

Cystic fibrosis, Bacterial septicemia, Endocarditis, Susceptible infections, Lower Respiratory Tract Infections, Gonorrhea, Skin and skin structure infections, Urinary tract infections, Bone and Joint Infections, Surgical Prophylaxis

Administration

IV Preparation Reconstitute infusion bottles with 100 mL of compatible diluent Reconstitute vials with a portion (usually 10 mL) of IV fluid withdawn from the IV container, dissolve, and return to container; repeat Reconstituted solutions are stable for 4 hours at room temperature and 24 hours refrigerated (4 C) in NS Normal color ranges from clear to yellow; these variations do not affect potency, but solution should be discarded if brown IV Administration Do not administer by IV push Final concentration should not exceed 5 mg/mL Infuse <500 mg over 20-30 minutes (15-30 minutes in children); infuse >500 mg over 40-60 min Vial contents must be transferred to 100 mL of infusion solution

Adult Dose

Lower Respiratory Tract, Skin/Skin Structure, & Gynecologic Infections Mild to moderate: 500-750 mg IV q12hr Intra-abdominal Infections Mild to moderate: 250-500 mg IV q6hr Severe: 500 mg IV q6hr or 1 g q8hr for 4-7 days, provided that infection is brought under control Pseudomonas Infections 500 mg IV q6hr; higher dosages may be administered, depending on organism sensitivity Urinary Tract Infections Uncomplicated: 250 mg IV q6hr Complicated: 500 mg IV q6hr Susceptible infections Moderate infections IV: Fully susceptible organisms: 500 mg IV q6-8hr Moderately susceptible organisms: 500 mg IV q6hr or 1 g IV q8hr Severe infections Fully susceptible organisms: 500 mg IV q6hr Moderately susceptible organisms: 1 g IV q6-8hr; not to exceed 50 mg/kg/day or 4 g/day, whichever is lower

Child Dose

Child: IV, IM 60–100 mg/kg/day q6h IM form not approved for <12 y

Renal Dose

Renal impairment: CrCl (ml/min) 31-70 500 mg every 6-8 hr 21-30 500 mg every 8-12 hr 6-20 250 mg or 3.5 mg/kg (whichever is lower) every 12 hr <5 Only give if haemodialysis started within 48 hr

Contraindication

Hypersensitivity.

Mode of Action

Imipenem is a potent inhibitor of bacterial cell wall synthesis and is bactericidal against a broad spectrum of pathogens. It is resistant to degradation by bacterial beta-lactamases. Cilastatin is an inhibitor of dehydropeptidase I, an enzyme found in the brush border of the renal tubules. It is given as the sodium salt with imipenem to prevent its renal metabolism and protect against nephrotoxic effects.

Precaution

Caution when used in patients with known hypersensitivity to other beta-lactams due to possibility of cross-sensitivity. CNS disorders such as epilepsy; renal, hepatic impairment; pregnancy, lactation. Lactation: Drug distributed in breast milk; use with caution

Side Effect

1-10% Phlebitis (2-5%),Eosinophilia (4%),Miscellaneous dermatologic effects (<3%),Potentially false-positive Coombs test (2%),Miscellaneous hematologic effects (<2%),Transient increase in blood urea nitrogen (BUN) or serum creatinine (<2%),Seizures (1.5%),Nausea, diarrhea, vomiting (1-2%) <1% Abnormal urinalysis,Agitation,Anaphylaxis,Anemia,Confusion (acute),Dizziness,Dyskinesia,Emergence of resistant strains of Pseudomonas aeruginosa,Fever,Hypersensitivity,Hypotension,Elevated liver function test (LFT) results,Increased prothrombin time (PT),Neutropenia (including agranulocytosis),Palpitations,Pruritus,Pseudomembranous colitis Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis.

Interaction

Concurrent admin with probenecid may increase the half-life of cilastatin. Increased risk of generalised seizures when used concurrently with ganciclovir.

Buy Imilast 500 from Arogga

In Bangladesh, you can get the original Imilast 500. Select your favorite one from a large collection of Medicine products. Order from App to get more offers and better experience.

What is the price of Imilast 500 in Bangladesh?

The latest price of Imilast 500 in Bangladesh is 1086.26৳. You can buy Imilast 500 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Asked Questions (FAQ)

Is Imilast 500 authentic?

Yes. Arogga sources Imilast 500 products from trusted suppliers, distributors, or manufacturers. Products are verified before delivery.

Does Arogga deliver all over Bangladesh?

Arogga delivers most products across Bangladesh. However, refrigerated or cold-chain medicines are delivered only within Dhaka. Delivery of some other products may also depend on product condition, storage requirements, and delivery location.

Is Cash on Delivery (COD) available for Imilast 500?

Yes. Cash on Delivery is available for all products in eligible locations across Bangladesh. Availability may vary depending on the product and delivery location.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on product availability, delivery location, and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy..

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Imilast 500. Please consult your doctor.
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CONSULT YOUR DOCTOR
Imilast 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Imilast 500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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UNSAFE
Imilast 500 may cause side effects which could affect your ability to drive. There are some side effects associated with this medicine (such as seeing, hearing, or feeling something that is not there) that may affect some patients' ability to drive.
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CAUTION
Imilast 500 should be used with caution in patients with kidney disease. Dose adjustment of Imilast 500 may be needed. Please consult your doctor.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Imilast 500 in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.