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Jexiline 250
Bristol Pharma Ltd.
Generic: Oxytetracycline
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Jexiline 250 does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Jexiline 250 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Jexiline 250 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE
Jexiline 250 does not usually affect your ability to drive.
UNSAFE
Jexiline 250 is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
UNSAFE
Jexiline 250 is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Medicine Overview of Jexiline 250mg Capsule
Introduction
Jexiline 250 is an antibiotic medicine used to treat bacterial infections in your body. It is effective in some infections of the lungs, urinary tract, eyes, and others. It kills bacteria, which helps to improve your symptoms and cure the infection. Jexiline 250 is also used to treat many sexually transmitted diseases. It helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) into a vein under the supervision of a healthcare professional. Your doctor will decide the correct dose for you. You should use this medicine regularly at evenly spaced intervals...
... Show moreUses of Jexiline 250
- Bacterial infections
Side effects of Jexiline 250
Common
- Photosensitivity
- Vomiting
- Nausea
- Diarrhea
How to use Jexiline 250
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Jexiline 250 works
Jexiline 250 is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.
Quick Tips
- Your doctor has prescribed Jexiline 250 to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Discontinue Jexiline 250 and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Brief Description
Indication
Acne, Susceptible infections, Uncomplicated gonorrhoea
Administration
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals.
Adult Dose
Oral
Susceptible infections
Adult: 250-500 mg 4 times daily. Max 4 g daily.
Acne
Adult: 250-500 mg bid.
Uncomplicated gonorrhoea
Adult: 1.5 g initially, followed by 0.5 g four times daily up to a total of 9 g per treatment course.
Intramuscular
Susceptible infections
Adult: 250 mg once daily or 300 mg daily in 2-3 divided doses.
Child Dose
Oral
Susceptible infections
Child: >8 yr: 25-50 mg/kg daily in 4 divided doses.
Intramuscular
Susceptible infections
Child: >8 yr: 15-25 mg/kg (max 250 mg) daily in 2-3 divided doses.
Renal Dose
Renal impairment: Dosage may need to be reduced.
Contraindication
Hypersensitivity to tetracyclines, children <8 yr, renal damage. Pregnancy, lactation.
Mode of Action
Oxytetracycline binds reversibly to the 30S and possibly 50S ribosomal subunits, thus inhibiting bacterial protein synthesis and arresting cell growth. It is active against a wide range of gram-positive and gram-negative organisms.
Precaution
Elderly, renal or hepatic impairment; myasthenia gravis; lupus erythematosus, children <12 yr.
Side Effect
Anorexia, nausea, vomiting,diarrhoea, glossitis, dysphagia, photosensitivity, oesphageal irritation and ulceration, nephrotoxicity, enterocolitis, rash (rare), blood dyscrasias. Headache, visual disturbances; intracranial hypertension; bulging fontanelles (infants).
Potentially Fatal: Rare. Fulminant diarrhoea in post operative patients.
Interaction
Antacids, iron, aluminum, calcium, magnesium, zinc salts reduce absorption. Concurrent use may cause increased levels of lithium, digoxin, halofantrine and theophylline; decreased concentrations of atovaquone. Increased risk of ergotism with ergot alkaloids. May cause failure of oral contraception.
Potentially Fatal: Interferes with anticoagulant control. Nephrotoxic effects exacerbated by diuretics, methoxyflurane or other nephrotoxic drugs; avoid concurrent use with potentially hepatotoxic drugs. Increased incidence of benign intracranial hypertension with retinoids.
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