Introduction
Appras 10 belongs to a group of medicines called antiplatelets or blood thinners. It helps prevent the formation of harmful blood clots and keeps the bl... View More
Uses of Appras 10
Side effects of Appras 10
How to use Appras 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Appras 10 may be taken wit... View More
How Appras 10 works
Appras 10 is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clot... View More
What if you forget to take Appras 10?
If you miss a dose of Appras 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your... View More
Indication
Acute coronary syndromes, thrombotic cardiovascular (CV) events, stent thrombosis, unstable angina (UA), non-ST-elevation myocardial infarction (NSTEMI)... View More
Administration
May be taken with or without food.
Adult Dose
Oral Acute coronary syndrome Adult: 60 mg as loading dose, followed by 10 mg once daily for up to 12 mth, given in combination w/ aspirin. Elderly: >... View More
Renal Dose
Renal impairment Dose adjustment not necessary
Contraindication
Active pathological bleeding such as peptic ulcer or intracranial hamorrhage. Patient with a history of prior transient ischemic attack or stroke
Mode of Action
Prasugrel is a prodrug that inhibits platelet activation and aggregation. The active metabolite irreversibly blocks the P2Y12 component of adenosine dip... View More
Precaution
Patient w/ propensity to bleed, low body wt (<60 kg). Patient who will undergo CABG and other surgical procedure; coronary angiography in UA/NSTEMI pati... View More
Side Effect
1-10% Bleeding,Anemia,Atrial fibrillation,Back pain,Bradycardia,Dizziness,Dyspnea,Headache,Hypertension,Nausea <1% Thrombotic thrombocytopenic purp... View More
Interaction
Increased risk of bleeding w/ oral anticoagulants (e.g. warfain), clopidogrel, NSAIDs and fibrinolytics.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More