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Nexataf25mg

Tablet
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Everest Pharmaceuticals Ltd.
Generic: Tenofovir Alafenamide
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nexataf. Please consult your doctor.
PregnancyPregnancy
SAFE IF PRESCRIBED
Nexataf is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Nexataf is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingDriving
UNSAFE
Nexataf may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Nexataf should be used with caution in patients with kidney disease. Dose adjustment of Nexataf may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Nexataf is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nexataf may not be needed in the... View More
descriptionMedical Overview

Introduction

Nexataf is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells.... View More

Uses of Nexataf

  • HIV infection
  • Chronic hepatitis B virus (HBV) infection

Side effects of Nexataf

Common
  • Headache

How to use Nexataf

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexataf is to be taken emp... View More

How Nexataf works

Nexataf is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears u... View More

What if you forget to take Nexataf?

If you miss a dose of Nexataf, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • You have been prescribed Tenvir AF 25mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
  • In combination with other medicines, it is used for the treatment of HIV infections.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Tenvir AF 25mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepat... View More
descriptionBrief Description

Indication

Chronic Hepatitis B Infection

Administration

Take with food

Adult Dose

Chronic Hepatitis B Infection Indicated for treatment of chronic hepatitis B virus (HBV) infection in adults with compensated liver disease 25 mg PO q... View More

Renal Dose

Renal impairment Mild, moderate, or severe: No dosage adjustment required ESRD (CrCl <15 mL/min): Use not recommended

Contraindication

Hypersensitivity

Mode of Action

Tenofovir alafenamide (AF) is a nucleotide reverse transcriptase inhibitor (NRTI) and a phosphonamidate prodrug of tenofovir Compared with tenofovir ... View More

Precaution

Lactic acidosis and severe hepatomegaly with steatosis, including fatalities, reported with nucleoside analogs, including tenofovir disoproxil fumarate ... View More

Side Effect

1-10% Headache (9%) ALT >5 x ULN (8%) Abdominal pain (7%) Fatigue (6%) Cough (6%) Glycosuria >3+ (5%) Nausea (5%) Back pain (5%)

Pregnancy Category Note

There are no human data on use in pregnant women to inform a drug-associated risks of adverse fetal developmental outcome In animal studies, no adver... View More

Interaction

Drugs that induce P-gp result in decreased tenofovir AF absorption and plasma concentrations, which may lead to loss of therapeutic effect (eg, carbamaz... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More