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Depram may cause excessive drowsiness with alcohol.
Depram may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing ... View More
Depram is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Depram may cause side effects which could affect your ability to drive. As Depram may impair your alertness or cause drowsiness or blurred vision, and t... View More
Depram should be used with caution in patients with kidney disease. Dose adjustment of Depram may be needed. Please consult your doctor.
Depram should be used with caution in patients with liver disease. Dose adjustment of Depram may be needed. Please consult your doctor. Regular monitori... View More
Depram is known as a tricyclic antidepressant. It is used to treat depression and bedwetting in children of age 6 years and above. It is also effective ... View More
Uses of Depram
Side effects of Depram
- Increased heart rate
- Blurred vision
- Dryness in mouth
- Difficulty in urination
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
How to use Depram
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depram may be taken with o... View More
How Depram works
Depram is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.... View More
What if you forget to take Depram?
If you miss a dose of Depram, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
- Depram is used for the treatment of depression and bedwetting in children.
- The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
- You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
- Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine.
- Do not drive or do anything that requires concentration until you know how this medicine affects you.
- Do not stop taking the medication suddenly without talking to your doctor.
Depression, Nocturnal enuresis
May be taken with or without food.
Oral Depression Adult: Initially, 75 mg in divided doses, may gradually increase to 150-200 mg daily as necessary. Max: 300 mg/day. May give in divide... View More
Oral Nocturnal enuresis Child: 6-7 yr 20-25 kg: 25 mg; 8-11 yr 25-35 kg: 25-50 mg; >11yr 35-54 kg: 50-75 mg. Doses are given just before bedtime... View More
Any degree of heart block or cardiac arrhythmias, recent MI, porphyria, narrow-angle glaucoma, urine retention, mania. Severe hepatic impairment. Childn... View More
Mode of Action
Imipramine is believed to increase the synaptic concentration of serotonin and/or norepinephrine in the CNS by inhibition of their reuptake by the presy... View More
Imipramine should be used cautiously and with close physician supervision in people, especially the elderly, who have benign prostatic hypertrophy, urin... View More
Orthostatic hypotension, HTN, tachycardia, palpitation, MI, arrhythmias, heart block, ECG changes, precipitation of CHF, stroke; confusional states (esp... View More
Increased plasma levels and effects with quinidine, cimetidine, SSRIs, propafenone, flecainide. Reduced plasma levels with barbiturates, phenytoin. May ... View More