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Duric100mg

Tablet
rx_reqRequire Prescription
Opsonin Pharma Limited
Generic: Allopurinol
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descriptionSafety Advices
AlcoholAlcohol
CAUTION
Caution is advised when consuming alcohol with Duric. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Duric may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing b... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Duric is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harm... View More
DrivingDriving
UNSAFE
Duric may cause side effects which could affect your ability to drive. Occasionally drowsiness, dizziness or vertigo, ataxia and visual disturbances, ma... View More
KidneyKidney
CAUTION
Duric should be used with caution in patients with kidney disease. Dose adjustment of Duric may be needed. Please consult your doctor.
LiverLiver
CAUTION
Duric should be used with caution in patients with liver disease. Dose adjustment of Duric may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Duric is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can appe... View More

Uses of Duric

  • Gout

Side effects of Duric

Common
  • Skin rash
  • Diarrhea
  • Nausea

How to use Duric

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duric is to be taken with ... View More

How Duric works

Duric is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

What if you forget to take Duric?

If you miss a dose of Duric, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your reg... View More

quick tipsQuick Tips
  • Your doctor has prescribed Duric to reduce episodes of gout attack.
  • Take Duric with food to avoid stomach upset.
  • Take plenty of fluids (2-3 litres) daily while on Duric.
  • Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Duric.
  • When you first start taking this medicine, you might have more gout attacks. Do not stop Duric on having an acute attack of gout as that could make an a... View More
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin... View More
  • Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
descriptionBrief Description

Indication

Adult: PO Gout; Hyperuricaemia Mild: 100 mg/day PO initially; increased weekly to 200-300 mg/day Moderate to severe: 100 mg/day PO initially; incre... View More

Administration

May inhibit the metabolism of mercaptopurine and azathioprine; reduce dose of mercaptopurine and azathioprine when given w/ allopurinol. May increase ef... View More

Adult Dose

Ensure adequate fluid intake. Prophylactically with an anti-inflammatory or colchicine for at least 1 mth. Withdraw immediately when sensitivity (skin r... View More

Renal Dose

Allopurinol is an inhibitor of the enzyme xanthine oxidase which converts hypoxanthine to xanthine then uric acid. The reduced production of uric acid r... View More

Mode of Action

Administration Should be taken with food. Take immediately after meals.

Precaution

Hyperuricaemia, Uric acid nephropathy, Cancer therapy-induced hyperuricaemia, Gout, Recurrent renal stones

Side Effect

Renal impairment: Haemodialysis: Administer dose after session or administer 50% supplemental dose. CrCl (ml/min) 10-20 200 mg daily. <3 100 mg da... View More

Pregnancy Category Note

1-10% Rash (1.5%),Nausea (1.3%),Renal failure (1.2%),Vomiting (1.2%) Frequency Not Defined Amblyopia,Arthralgias,Blood dyscrasias,Bronchospasm,Card... View More

Interaction

Hypersensitivity; acute attack of gout.

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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