HomeLab TestAnti-Mitochondrial Antibody
Overview
Primary Biliary Cholangitis (PBC):
AMA is a hallmark of PBC, a chronic autoimmune liver disease characterized by inflammation and destruction of small bile ducts within the liver.
PBC primarily affects middle-aged women, and its progression can lead...
Risk assessment
While the presence of AMA is strongly associated with PBC, it's not a definitive indicator of disease development. Some individuals with AMA may never develop PBC, while others may progress to clinical disease over time.
Additional factors such as ot...
Ranges
Negative Result: If the test comes back negative, it usually means that there are no detectable anti-mitochondrial antibodies in the blood. However, it's important to note that a small percentage of people with PBC may still have negative AMA test re...
Test result interpretation
Negative Result: If the test comes back negative, it usually means that there are no detectable anti-mitochondrial antibodies in the blood. However, it's important to note that a small percentage of people with PBC may still have negative AMA test re...
Sample types
Blood sample.
Frequently Asked Questions
What is the prognosis for someone with PBC?
What is Primary Biliary Cholangitis (PBC)?
What does a positive AMA test indicate?
Can a person have PBC without positive AMA?
Can lifestyle changes help manage PBC?
What are Anti-Mitochondrial Antibodies (AMA)?
What are the symptoms of PBC?
What are the risk factors for developing PBC?
What research is being done on AMA and PBC?
How is AMA testing performed?
How is PBC treated?
Are there any complications associated with PBC?
Anti-Mitochondrial Antibody
Understanding AMA, its Role in Diagnosing Primary Biliary Cholangitis, and its Clinical Implications
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Sample Type:
blood
Fasting Required:
No
Description
Anti-Mitochondrial Antibodies (AMA) are autoantibodies directed against proteins in the mitochondria, the energy-producing structures within cells. They are primarily associated with Primary Biliary Cholangitis (PBC), an autoimmune liver disease. Detection of AMA in the blood is a key marker for diagnosing PBC, and testing is usually done when a person exhibits symptoms or has abnormal liver function tests.